Ergotamine misuse
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Ergotism: case report A 59-year-old man developed ergotism following self-administration of ergotamine (drug misuse) for headache and photophobia. The man experienced headache and photophobia 7 days previously for which he self-administered ergotamine [route and dosage not stated] for 5 days (drug misuse), and on the 6th day, he presented to hospital with phosphenes, nausea, syncope, diaphoresis and typical precordial angina with spontaneous remission. After 24 hours, he experienced neurological deterioration. Also, it was reported that he developed hypotension, bradycardia and ST segment elevation of the inferior wall. Coronary angiography showed no coronary stenosis. The man was treated with unspecified inotropes and liquids, but he continued to exhibit refractory hypotension. Cerebral tomography showed no abnormalities. A suspicion of ergotism was made. Therefore, he was treated with nitroglycerin. Subsequently, a gradual improvement of his neurological conditions and cardiovascular state was observed along with a single sequela of incomplete left homonymous hemianopsia. Macedo-Calvillo L, et al. Intoxication by ergotamine. Diagnostic and therapeutic implication. Medicina Interna de Mexico 36: 418-423, No. 3, May-Jun 2020. Available from: 803502518 URL: http://doi.org/10.24245/mim.v36i3.2986 [Spanish; summarised from an English abstract]
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Reactions 26 Sep 2020 No. 1823
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