High-Dimensional Single Cell Analysis Mass Cytometry, Multi-parametr
This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques f
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Harris G. Fienberg Garry P. Nolan Editors
High-Dimensional Single Cell Analysis Mass Cytometry, Multi-parametric Flow Cytometry and Bioinformatic Techniques
Current Topics in Microbiology and Immunology Volume 377
Series editors Klaus Aktories
Medizinische Fakultät, Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Abt. I AlbertLudwigs-Universität Freiburg, Albertstr. 25, 79104 Freiburg, Germany Richard W. Compans Department of Microbiology and Immunology, Emory University, 1518 Clifton Road, CNR 5005, Atlanta, GA 30322, USA Max D. Cooper Department of Pathology and Laboratory Medicine, Georgia Research Alliance, Emory University, 1462 Clifton Road, Atlanta, GA 30322, USA Jorge E. Galan Boyer Ctr. for Molecular Medicine, School of Medicine, Yale University, 295 Congress Avenue, room 343, New Haven, CT 06536-0812, USA Yuri Y. Gleba ICON Genetics AG, Biozentrum Halle, Weinbergweg 22, 06120 Halle, Germany Tasuku Honjo
Faculty of Medicine, Department of Medical Chemistry, Kyoto University, Sakyo-ku, Yoshida, Kyoto 606-8501, Japan Yoshihiro Kawaoka School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI 53706, USA Bernard Malissen
Centre d’Immunologie de Marseille-Luminy, Parc Scientifique de Luminy, Case 906, 13288 Marseille Cedex 9, France Michael B. A. Oldstone Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA Rino Rappuoli Novartis Vaccines, Via Fiorentina 1, Siena 53100, Italy Peter K. Vogt Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC-239, La Jolla, CA 92037, USA Honorary Editor: Hilary Koprowski (deceased) Formerly at Biotechnology Foundation, Inc., Ardmore, PA, USA
For further volumes: http://www.springer.com/series/82
Harris G. Fienberg Garry P. Nolan •
Editors
High-Dimensional Single Cell Analysis Mass Cytometry, Multi-parametric Flow Cytometry and Bioinformatic Techniques Responsible Series Editor: Bernard Malissen
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Editors Harris G. Fienberg Garry P. Nolan Department of Microbiology and Immunology Center for Clinical Sciences Research Stanford School of Medicine Stanford, CA USA
ISSN 0070-217X ISSN 2196-9965 (electronic) ISBN 978-3-642-54826-0 ISBN 978-3-642-54827-7 (eBook) DOI 10.1007/978-3-642-54827-7 Springer Heidelberg New York Dordrecht London Library of Congress Control Number: 2014936870 Springer-Verlag Berlin Heidelberg 2014 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or s
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