Molecular Biology of Hemopoiesis Proceedings of the Third Annual Sym

Perhaps no scientific field in recent years has gained in techniques and applications as much as molecular biology, and it is certainly no ex­ aggeration to·say that among all the applications of molecular biology, hematology in general, and hemopoiesis i

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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: NATHAN BACK, State University of New York at Buffalo IRUN R. COHEN, The Weizmann Institute of Science DAVID KRITCHEVSKY, Wistar Institute ABEL LAJTHA, N. S. Kline Institute for Psychiatric Research ROOOLFO PAOLETTI, University of Milan

Recent Volumes in this Series Volume 234 BIOLOGY OF GROWTH FACTORS: Molecular Biology, Oncogenes, Signal Transduction, and Clinical Implications Edited by Jeffrey E. Kudlow, David H. MacLennan, Alan Bernstein, and Avrum I. Gotlieb Volume 235 CENTRAL DI DOPAMINE RECEPTORS Edited by Menek Goldstein, Kjell Fuxe, and Irving Tabachnick Volume 236 NEURORECEPTORS AND SIGNAL TRANSDUCTION Edited by Shozo Kito, Tomio Segawa, Kinya Kuriyama, Masaya Tohyama, and Richard W. Olsen Volume 237 HISTOPHYSIOLOGY OF THE IMMUNE SYSTEM: The Life History, Organization, and Interactions of Its Cell Populations Edited by Sigbj0rn Fossum and Bent Rolstad Volume 238 BIOTECHNOLOGICAL APPLICATIONS OF LIPID MICROSTRUCTURES Edited by Bruce Paul Gaber, Joel M. Schnur, and Dennis Chapman Volume 239 HOST DEFENSES AND IMMUNOMODULATION TO INTRACELLULAR PATHOGENS Edited by Toby K. Eisenstein, Ward E. Bullock, and Nabil Hanna Volume 240 PROTEASES: Potential Role in Health and Disease II Edited by Walter H. Hor! and August Heidland Volume 241 MOLECULAR BIOLOGY OF HEMOPOIESIS Edited by Mehdi Tavassoli, Esmail D. Zanjani, Joao L. Ascensao, Nader G. Abraham, and Alan S. Levine

A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon pUblication. Volumes are billed only upon actual shipment. For further information please contact the publisher.

MOLECULAR BIOLOGY OF HEMOPOIESIS Edited by

Mehdi Tavassoli Veterans Administration Medical Center University of Mississippi Jackson, Mississippi

Esmail D. Zanjani Veterans Administration Medical Center University of Nevada Reno, Nevada

Joao L. Ascensao and Nader G. Abraham New York Medical College Valhalla, New York

and

Alan S. Levine National Heart, Lung, and Blood Institute DiVision of Blood Diseases and Resources Bethesda, Maryland

PLENUM PRESS • NEW YORK AND LONDON

Library of Congress Cataloging in Publication Data Symposium on Molecular Biology of Hemopoiesis (3rd: 1987: Rye Brook, N.Y.) Molecular biology of hemopoiesis I edited by Mehdi Tavassoli ... let al.]. p. cm. -(Advances in experimental medicine and biology; v. 241) "Proceedings of the Third Annual Symposium on Molecular Biology of Hemopoiesis, held November 6-7,1987, in Rye Brook, New York"- T.p. verso. Dedicated to the centennial of the National Institutes of Health. Includes bibliographies and index. ISBN 978-1-4684-5573-1 ISBN 978-1-4684-5571-7 (eBook) DOl 10.1007/978-1-4684-5571-7

1. Hematopoiesis-Congresses. 2. Molecular biology-Congresses. 3. National Institutes of Health (U.S.)-Congresses.1. Title. II. Series. [DNLM: 1. Hematopoiesis-congresses. 2. Hematopoietic Stem Cells-congresses. 3. Molecularbiologyo-congresses. WI AD559v. 241 I WH 140S9894m 1987] QP92.S95 198