MRS Communications
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Impact Factor
2018 • Volume 8, Issue 3
3.01
To view additional abstracts and gain access to Prospectives Articles, Commentaries and Research Letters, visit www.mrs.org/mrc.
SPECIAL ISSUE PROSPECTIVE ARTICLES: 2D NANOMATERIALS FOR HEALTHCARE AND LAB-ON-A-CHIP DEVICES Intracellular microRNA quantification in intact cells: a novel strategy based on reduced graphine oxide-based fluorescence quenching. Ramasamy Paulmurugan, Stanford University School of Medicine, USA; Pulickel M. Ajayan, Rice University, USA; Dorian Liepmann, University of California, Berkeley, USA; and V. Renugopalakrishnan, Harvard Medical School and Northeastern University, USA Nanomaterials have been proposed as key components in biosensing, imaging, and drug delivery since they offer distinctive advantages over conventional approaches. The unique chemical and physical properties of graphene make it possible to functionalize and develop protein transducers, therapeutic delivery vehicles, and microbial diagnostics. In this study, reduced graphene oxide as a potential nanomaterial for quantification of microRNAs including their structural differentiation in vitro in solution and inside intact cells are evaluated. Results provide evidence for the potential use of graphene nanomaterials as a platform for developing devices that can be used for microRNA quantitation as biomarkers for clinical applications. DOI:org/10.1557/mrc.2018.120
Nickel-reduced graphene oxide composite foams for electrochemical oxidation processes: towards biomolecule sensing S. Thoufeeq, Cochin University of Science and Technology, India; Pankaj Kumar Rastogi and Narayanaru Sreekanth, Tata Institute of Fundamental Research, India; Anantharaman Malie Madom Ramaswamy Iyer, Cochin University of Science and Technology, India; and Tharangattu N. Narayanan, Tata Institute of Fundamental Research, India Metal–graphene composites are sought after for various applications. A hybrid light-weight foam of nickel (Ni) and reduced graphene oxide (rGO), called Ni-rGO, is reported here for small molecule oxidations and thereby their sensing.
Methanol oxidation and non-enzymatic glucose sensing are attempted with the Ni-rGO foam via electrocatalytically, and an enhanced methanol oxidation current density of 4.81 mA/ cm2 is achieved, which is ~1.7 times higher than that of bare Ni foam. In glucose oxidation, the Ni-rGO electrode shows a better sensitivity over bare Ni foam electrode where it could detect glucose linearly over a concentration range of 10 µM to 4.5 mM with a very low detection limit of 3.6 µM. This work demonstrates the synergistic effects of metal and graphene in oxidative processes, and also shows the feasibility of scalable metal–graphene composite inks development for small molecule printable sensors and fuel cell catalysts. DOI:org/10.1557/mrc.2018.123
Flexible substrate sensors for multiplex biomarker monitoring Desmond Brennan and Paul Galvin, Tyndall National Institute, University College, Ireland Wearable healthcare technologies should be non-invasive, robust to daily
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