Multidimensional Prognostic Index (MPI) in elderly patients with acute myocardial infarction

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ORIGINAL ARTICLE

Multidimensional Prognostic Index (MPI) in elderly patients with acute myocardial infarction Valeria Cammalleri1   · Michela Bonanni1 · Francesca Maria Bueti1 · Andrea Matteucci1 · Lisa Cammalleri2 · Giuseppe Stifano1 · Saverio Muscoli1 · Francesco Romeo1 Received: 7 July 2020 / Accepted: 16 September 2020 © The Author(s) 2020

Abstract Background  Management of elderly patients with acute myocardial infarction (AMI) is challenging due to lack of knowledge about the link between fragility, outcomes and interventional procedures. Aims  The aim of this study was to establish the prognostic role of the Multidimensional Prognostic Index (MPI) in elderly with AMI. Methods  A total of 241 patients ≥ 65 years old with AMI were continuously enrolled in this prospective study and divided into three groups according to the MPI score. The primary endpoint was 30-day mortality. Secondary endpoints were 6-month mortality and rate of adverse events. Results  In-hospital overall mortality rate was higher in MPI-3 (p = 0.009). Patients of MPI-3 had a significantly higher mortality rate regarding the primary endpoint with 30-day survival of 78.9%, compared to 97.4% and 97.2%, in MPI-1, MPI-2 (p