Muscle Metabolism During Exercise Proceedings of a Karolinska Instit

Howard G. Knuttgen of Biology, Boston University, 2 Cummington Department Street, Boston, 02215 Massachusetts, USA The relationship of the formation of lactate acid to skeletal muscle energy release in exercising humans was first explored by A. V. Hill an

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ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY Editorial Board: Nathan Back

Chairman. Department of Biochemical Pharmacology. School of Pharmacy. State University of New York. Buffalo. New York

N. R. Di Luzio

Chairman. Department of Physiology. Tulane University School of Medicine. New Orleans. Louisiana

Alfred Gellhorn

University of Pennsylvania Medical School. Philadelphia. Pennsylvania

Bernard Halpern

College de France. Director 01 the Institute ollmmuno.Biology. Paris. France

Ephraim Katchalski

Department of Biophysics. The Weizmann Institute of Science. Rehovoth.lsrael

David Kritchevsky

Wistar Institute. Philadelphia. Pennsylvania

Abel Lajtha

New York State Research Institute lor Neurochemistry and Drug Addiction. Ward's Island. New York

Rodolfo Paoletti

Institute of Pharmacology. University of Milan. Milan. Italy

Volume 1 THE RETICULOENDOTHELIAL SYSTEM AND ATHEROSCLEROSIS Edited by N. R. Di Luzio and R. Paoletti· 1967 Volume 2 PHARMACOLOGY OF HORMONAL POLYPEPTIDES AND PROTEINS Edited by N. Back, L. Martini, and R. Paoletti' 1968 Volume 3 GERM·FREE BIOLOGY-Experimental and Clinical Aspects Edited by E. A. Mirand and N. Back· 1969 Volume 4 DRUGS AFFECTING LIPID METABOLISM Edited by W. L. Holmes, L. A. Carlson, and R. Paoletti' 1969

Volume 8 BRADYKININ AND RELATED KININS: Cardiovascular, Biochemical, and Neural Actions Edited by F. Sicuteri, M. Rocha e Silva, and N. Back' 1970 Volume 9 SHOCK: Biochemical, Pharmacological, and Clinical Aspects Edited by A. Bertelli and N. Back· 1970 Volume 10 THE HUMAN TESTIS Edited by E. Rosemberg and C. A. Paulsen' 1970 Volume 11 MUSCLE METABOLISM DURING EXERCISE Edited by B. Pernow and B. Saltin • 1971

VolumeS LYMPHATIC TISSUE AND GERMINAL CENTERS IN IMMUNE RESPONSE Edited by L. Fiore·Donati and M. G. Hanna, Jr.• 1969

Volume 12 MORPHOLOGICAL AND FUNCTIONAL ASPECTS OF IMMUNITY Edited by K. Lindahl.Kiessling, G. Aim. and M. G. Hanna, Jr.• 1971

Volume 6 RED CELL METABOLISM AND FUNCTION Edited by George J. Brewer· 1970

Volume 13 CHEMISTRY AND BRAIN DEVELOPMENT Edited by R. Paoletti and A. N. Davison' 1971

Volume 7 SURFACE CHEMISTRY OF BIOLOGICAL SYSTEMS Edited by Martin Blank • 1970

Volume 14 MEMBRANE.BOUND ENZYMES Edited by G. Porcellati and F. di Jeso· 1971

Muscle Metabolism During Exercise Proceedings of a Karolinska Institutet Symposium held in Stockholm, Sweden, September 6-9, 1970 Honorary guest: E. Hohwii Christensen

Edited by

Bengt Pernow Associate Professor and Chairman Department of Clinical Physiology Sera/imerlasarettet, Karolinska Institutet Stockholm, Sweden

and

Bengt Saltin Associate Professor Department of Physiology Gymnastik & Idrottshiigskolan Stockholm, Sweden

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PLENUM PRESS • NEW YORK·LONDON • 1971

First Printing-February 1971 Second Printing-January 1974

Library of Congress Catalog Card Number 71·148821 ISBN-13: 978-1-4613-4611-1 e-ISBN: 978-1-4613-4609-8 DOl: 10.1007/978-1-4613-4609-8

© 1971 Plenum Press, New York

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