Mycobacterium tuberculosis Interactions with the Immune System
Tuberculosis once again occupies a special position in the areas of infec tious diseases and microbiology. This disease has been important to mankind since even before biblical times. Tuberculosis has been a major cause of morbidity and mortality in huma
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		    INFECTIOUS AGENTS AND PATHOGENESIS Series Editors: Mauro Bendinelli, University of Pisa Herman Friedman, University of South Florida
 
 COXSACKIEVIR USES A General Update Edited by Mauro Bendinelli and Herman Friedman
 
 MYCOBACTERIUM TUBERCULOSIS Interactions with the Immune System Edited by Mauro Bendinelli and Herman Friedman
 
 Mycobacterium tuberculosis INTERACTIONS WITH THE IMMUNE SYSTEM
 
 Edited by
 
 Mauro Bendinelli University oj Pisa Pisa, Italy
 
 and
 
 Herman Friedman University oj South Florida Tampa, Florida
 
 Plenum Press • N ew York and London
 
 Library of Congress Cataloging in Publication Data Mycobacterium tuberculosis: interactions with the immune system / edited by Mauro
 
 Bendinelli and Herman Friedman. p. cm. -(Infectious agents and pathogenesis) Includes bibliographical references and index.
 
 ISBN-13: 978-1-4684-5420-8 e-ISBN-13: 978-1-4684-5418-5 DO!: 10.1 007/ 978-1-4684-5418-5 1. Tuberculosis-Immunological aspects. 2. Mycobacterium tuberculosis. I. Bendinelli, Mauro. II. Friedman, Herman, 1931. III. Series. QR20l.T6M93 1988 616'.0142-dc19 88-4128 CIP
 
 © 1988 Plenum Press, New York Softcover reprint of the hardcover 1st edition 1988 A Division of Plenum Publishing Corporation 233 Spring Street, New York, N.Y. 10013 All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher
 
 Contributors
 
 L. F. AFFRONTI • Department of Microbiology, The George Washington University Medical Center, Washington, D. C. 20037 MARCELLO BAGNASCO • Allergy Center-Scientific Institute of Internal Medicine, University of Genoa, 16132 Genoa, Italy GIOIA BENEDETTINI • Institute of Microbiology, University of Pisa, 56100 Pisa, Italy ELLEN BUSCHMAN • Department of Medicine, McGill University, Montreal General Hospital Research Institute, Montreal, Quebec, H3G lA4 Canada MARIO CAMPA • Institute of Microbiology, University of Pisa, 56100 Pisa, Italy GIORGIO WALTER CANONICA • Allergy Center-Scientific Institute of Internal Medicine, University of Genoa, 16132 Genoa, Italy FRANK M. COLLINS • Trudeau Institute, Inc., Saranac Lake, New York 12983 ALFRED J. CROWLE • Department of Microbiology and Immunology, Webb-Waring Lung Institute, University of Colorado Health Sciences Center, Denver, Colorado 80262 GENNARO DE LlBERO • Max-Planck-Institut fur Immunbiologie, D-7800, Freiburg, Federal Republic of Germany ASIM K. DUTT • Alvin C. York Veterans Administration Medical Center, Murfreesboro, Tennessee, 37130; Department of Medicine, Meharry Medical College, Nashville, Tennessee 37208 MARK L. EDWARDS • Department of Medical Microbiology, University of Wisconsin-Madison, Madison, Wisconsin 53706 JERROLD J. ELLNER • Case Western Reserve University and University Hospitals of Cleveland, Cleveland, Ohio 44106 v
 
 VI
 
 CONTRIBUTORS
 
 MAYER B. GOREN • Department of Molecular and Cellular Biology, National Jewish Center for Immunology and Respiratory Medici		
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