Myelin Basic and Clinical Advances

This book presents the latest exciting advances in understanding of the structure and function of myelin in the central and peripheral nervous systems under normal and pathological conditions. Readers will find state of the art information from the perspe

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Kazunori Sango Junji Yamauchi Toru Ogata Keiichiro Susuki Editors

Myelin

Basic and Clinical Advances

Advances in Experimental Medicine and Biology Volume 1190 Series Editors Wim E. Crusio CNRS and University of Bordeaux UMR 5287, Institut de Neurosciences Cognitives et Intégratives d’Aquitaine, Pessac Cedex, France John D. Lambris University of Pennsylvania, Philadelphia, PA, USA Nima Rezaei Children’s Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran

More information about this series at http://www.springer.com/series/5584

Kazunori Sango • Junji Yamauchi • Toru Ogata • Keiichiro Susuki Editors

Myelin Basic and Clinical Advances

Editors Kazunori Sango Diabetic Neuropathy Project, Department of Sensory and Motor Systems Tokyo Metropolitan Institute of Medical Science Tokyo, Japan

Junji Yamauchi Laboratory of Molecular Neuroscience and Neurology Tokyo University of Pharmacy and Life Science Hachioji, Tokyo, Japan

Toru Ogata Department of Rehabilitation for the Movement Functions Research Institute, National Rehabilitation Center Tokorozawa, Saitama, Japan

Keiichiro Susuki Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine Wright State University Dayton, OH, USA

ISSN 0065-2598 ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-981-32-9635-0 ISBN 978-981-32-9636-7 (eBook) https://doi.org/10.1007/978-981-32-9636-7 # Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Preface

The successful publication of our previous book entitled Schwann Cell Development and Pathology (Kazunori Sango and Junji Yamauchi (eds) 2014), which ha