Oxaliplatin
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Anaphylactic shock: case report A 70-year-old woman developed anaphylactic shock during treatment with oxaliplatin for metastatic rectal cancer. The woman, who was diagnosed with rectal cancer with a right adrenal gland metastasis, started receiving oxaliplatin [route and dosage not stated] and capecitabine. However, oxaliplatin was discontinued in the 3rd cycle because of anaphylactic shock caused by oxaliplatin [duration of treatment to reaction onset and outcome not stated]. The right adrenal metastasis had decreased in size after 2 cycles of oxaliplatin and capecitabine. At 3 months after the diagnosis, the woman underwent an abdominoperineal resection with D2 (proxD3) lymph node dissection and right adrenalectomy. According to the TNM classification of malignant tumours, stage IVA metastatic rectal cancer was diagnosed. The chemotherapy with capecitabine was administered every 3 weeks for 12 months after the index surgery. At 18 months after the surgery, she was alive with no evidence of recurrence and distant metastasis. Hayashi H, et al. Complete resection of rectal cancer with a synchronous solitary adrenal metastasis: A case report. International Journal of Surgery Case Reports 75: 242-245, 803507248 2020. Available from: URL: http://doi.org/10.1016/j.ijscr.2020.09.094
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Reactions 17 Oct 2020 No. 1826
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