Polymers against Microorganisms On the Race to Efficient Antimicrobi

This book provides an introductory and general overview of advances in polymers towards their employment as antimicrobial materials. The author describes current approaches for avoiding microbial contamination, toward macro-molecular antibiotics, and prev

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olymers against Microorganisms On the Race to Efficient Antimicrobial Materials

Polymers against Microorganisms

Juan Rodríguez-Hernández

Polymers against Microorganisms On the Race to Efficient Antimicrobial Materials

Juan Rodríguez-Hernández Institute of Polymer Science & Technology (ICTP-CSIC) Madrid, Spain

ISBN 978-3-319-47960-6 ISBN 978-3-319-47961-3 DOI 10.1007/978-3-319-47961-3

(eBook)

Library of Congress Control Number: 2016954979 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

Bacterial contamination is still an unresolved problem present in cases in which a biomaterial is required. This is an issue independent of the biomaterial considered and is particularly serious in those cases in which long-term implants are employed. In this context, polymers have been proposed as interesting candidates to improve the biomaterial performance in order to prevent microbial contamination. Different previous books have been published focusing their efforts on one of the aspects of antimicrobial polymers: the synthesis, in the biology of the microorganisms in contact with synthetic materials or related to their final use (e.g., food packaging). This book aims to present a complete overview of this rapidly evolving field providing a concise, clear, and precise image of the most important aspects involved in the use of polymers to combat microorganisms. As will be depicted throughout this book, polymers’ mode of action relies on physiochemical parameters such as hydrophobicity and cationic charge, rather than specific receptor-mediated interactions, so the activity of the polymers can be modulated by tuning key structural parameters. Taking into account the mechanism of action, polymers exhibit important advanta