Prevalence of metabolic syndrome in children aged 5-9 years from southwest colombia: a cross-sectional study

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Prevalence of metabolic syndrome in children aged 5-9 years from southwest colombia: a cross-sectional study Milton Fabian Suarez-Ortegón, Cecilia Aguilar-de Plata Cali, Colombia

Methods: A total of 494 children were evaluated. Multivariate models with filtered variables in preliminary univarite analyses were built to find predictive factors of MetS and its components. Results: The prevalence of MetS was 8.7% in the studied children. Multivariate models showed that age, overweight and low socioeconomic stratum were associated with MetS; low high-density lipoprotein cholesterol was not significantly associated with any variable; high triglycerides were positively associated with age, overweight and inversely associated with kilocalories/day; female gender was the only variable significantly associated with high fasting glucose (inverse association); and age, gender and overweight were significant factors for increased waist circumference. In the case of high blood pressure, no variable was classified to the multivariate analysis. Conclusions: This study showed disturbing figures regarding cardiometabolic risk in the children based on comparisons with studies in adolescents. Further studies

Author Affiliations: Centre for Population Health Sciences, University of Edinburgh, Edinburgh (Suarez-Ortegón MF); Nutrition Group, University of Valle, Cali, Colombia (Suarez-Ortegón MF, Aguilar-de Plata C); Physiological Sciences Department, University of Valle, Cali, Colombia (Aguilar-de Plata C) Corresponding Author: Milton Fabian Suarez-Ortegón, MSc, Center for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, United Kingdom (Tel: 0131 650 1000; Fax: 0131 650 6909; Email: [email protected]) doi: 10.1007/s12519-016-0008-z ©Children's Hospital, Zhejiang University School of Medicine, China and Springer-Verlag Berlin Heidelberg 2016. All rights reserved.

World J Pediatr, Online First, January 2016 . www.wjpch.com

are needed to confirm the utility of the de Ferranti Mets definition in children. World J Pediatr January 2016; Online First Key words: fasting glucose; metabolic syndrome; obesity

Introduction

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ardiometabolic diseases (CMD) as hypertension, type 2 diabetes, and cardiac and cerebrovascular disease are a group of disorders associated with environmental and genetic factors, and burden of these diseases has increased in developing countries in recent years.[1,2] The establishment of CMD in adults is the result of pathological chronic processes that can start in early life stages.[3] Currently, obesity, a well-known factor associated to CMD developing, is increasingly reported as a public health problem in children and adolescents.[4,5] Metabolic syndrome (MetS), defined as the combination of abdominal obesity and alterations in glycemia, blood lipids and blood pressure, is a predictor of increased risk for CMD. There are several definitions and criteria for this syndrome in adults, [6-8] a few definitions for adolescents[9-11] bu