Psychometric properties of the EuroQol Five Dimensional Questionnaire (EQ-5D-3L) in caregivers of autistic children
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Psychometric properties of the EuroQol Five Dimensional Questionnaire (EQ-5D-3L) in caregivers of autistic children Rahul Khanna • Krutika Jariwala John P. Bentley
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Accepted: 20 April 2013 Ó Springer Science+Business Media Dordrecht 2013
(convergent validity) was observed among EQ-5D-3L index and VAS and (SF-12v2) physical component summary and mental component summary scores. Caregivers’ EQ-5D-3L index and VAS scores varied by levels of autism severity among care recipients, providing evidence of known-groups validity. Reliability assessed through Cronbach’s alpha was less than satisfactory; however, corrected item-total correlations were adequate. Conclusions The EQ-5D-3L is a psychometrically sound tool to elicit health state preferences among caregivers of children with autism.
Abstract Purpose This study aimed to ascertain the psychometric properties of EuroQol Five Dimensional Questionnaire (EQ-5D-3L) in primary caregivers of children with autism. The convergent validity, discriminant validity, knowngroups validity, internal consistency reliability, and floor and ceiling effects of EQ-5D-3L were analyzed. Methods A cross-sectional design was used for study purposes. Through an online survey, relevant study information was collected from 316 primary caregivers of children with autism. Study participants were from families of children with autism living in the United States who were registered with the Interactive Autism Network. Convergent validity of the EQ-5D-3L was assessed through its correlation with other measures of similar constructs. Discriminant validity was assessed by observing the correlation of EQ-5D-3L domains with theoretically unrelated constructs. Known-groups validity was tested by comparing EQ-5D-3L index and visual analog scale (VAS) scores across levels of autism severity among the care recipients. Internal consistency reliability of EQ-5D-3L was tested. Lastly, floor and ceiling effects of EQ-5D-3L were assessed. Results More than 60 % of participants reported problems of ‘anxiety/depression.’ Convergent and discriminant validity of the EQ-5D-3L was good. Significant correlation
Keywords Reliability
R. Khanna (&) K. Jariwala J. P. Bentley Department of Pharmacy Administration, School of Pharmacy, The University of Mississippi, Faser Hall Room 236, PO Box 1848, University, MS 38677, USA e-mail: [email protected]
Introduction
R. Khanna J. P. Bentley Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, USA
Autism Caregivers EQ-5D-3L Validity
Abbreviations EQ-5D-3L EuroQol Five Dimensional Questionnaire VAS Visual analog scale IAN Interactive Autism Network PDD-NOS Pervasive developmental disorder-not otherwise specified CDC Centers for Disease Control and Prevention HRQOL Health-related quality of life CGSQ Caregiver Strain Questionnaire SCQ Social Communication Questionnaire SF-12v2 Medical Outcomes Study Short-Form Health Survey version 2
Autism is a neurodevelopmental disorder with the hallmark sympt
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