Recent approaches in clinical applications of 3D printing in neonates and pediatrics

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Recent approaches in clinical applications of 3D printing in neonates and pediatrics Sukanya V S 1 & Nalinikanta Panigrahy 2 & Subha Narayan Rath 1 Received: 17 July 2020 / Revised: 18 September 2020 / Accepted: 22 September 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Neonates and pediatric populations are vulnerable subjects in terms of health. Proper screening and early optimal treatment would reduce infant and child mortality, improving the quality of life. Researchers and clinicians all over the world are in pursuit of innovations to improve the medical care delivery system. Infant morphometrics changes drastically due to the rapid somatic growth in infancy and childhood, demanding for patient-specific customization of treatment intervention accordingly. 3D printing is a radical technology that allows the generation of physical 3D products from digital images and addresses the patient-specific requirement. The combination of cost-effective and on-demand customization offers a boundless opportunity for the enhancement of neonates and pediatric health. Conclusion: The advanced technology of 3D printing proposes a pioneering breakthrough in bringing physiologically and anatomically appropriate treatment strategies addressing the unmet needs of child health problems. What is Known: • The potential application of 3D printing is observed across a multitude of fields within medicine and surgery. • The unprecedented effect of this technology on pediatric healthcare is still very much a work in progress. What is New: • The recent clinical applications of 3D printing provide better treatment modalities to infants and children. • The review provides an overview of the comparison between conventional treatment methods and 3DP regarding specific applications

Keywords 3D printing . Neonatal and pediatric care . Surgical models . Bronchomalacia . Congenital diseases Abbreviations 3DP 3 dimensional printing Communicated by Daniele De Luca * Subha Narayan Rath [email protected] Sukanya V S [email protected] Nalinikanta Panigrahy [email protected] 1

Department of Biomedical Engineering, Indian Institute of Technology Hyderabad (IITH), Kandi , Sangareddy, Telangana 502285, India

2

Department of Neonatology, Rainbow Children’s Hospital, Hyderabad, India

CADD CPAP CT DICOM FDM MRI

Computer-aided design and drafting Continuous positive airway pressure Computed tomography Digital image and communication in medicine Fusion deposition modeling Magnetic resonance imaging

Introduction According to WHO reports in 2018, it was estimated that 2.6 million children died in the first month of their life across the globe [1]. The major cause of death amongst neonates and children under the age of 12 include preterm birth, congenital anomalies, infections, birth asphyxia, and malnutrition [2]. Preterm neonates are susceptible to have complications

Eur J Pediatr

influencing pediatric health. Infants born with congenital anomalies and surgical conditions pose a real threat in the e