Red cell differential width (RDW) as a predictor of survival outcomes with palliative and adjuvant chemotherapy for meta

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UROLOGY - ORIGINAL PAPER

Red cell differential width (RDW) as a predictor of survival outcomes with palliative and adjuvant chemotherapy for metastatic penile cancer Reena Patel1 · Louise English2 · Wing K. Liu3 · Alison C. Tree4 · Benjamin Ayres2 · Nick Watkin2 · Lisa M. Pickering3,4 · Mehran Afshar1,3 Received: 18 June 2020 / Accepted: 6 July 2020 © The Author(s) 2020

Abstract Purpose  Red cell distribution width (RDW) measures red cells’ size variability. Metastatic penile cancer displays poor chemotherapy response. As no validated prognostic predictor exists, we investigated whether RDW correlates independently with survival outcomes in metastatic penile cancer treated by chemotherapy. Methods  Electronic chemotherapy files of patients with metastatic penile cancer (M1 or N3) from a large academic supraregional centre were retrospectively analysed between 2005 and 2018. Patients were stratified into RDW > 13.9% and