Relationship of dietary and serum zinc and leptin levels with protein energy wasting in haemodialysis patients
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NEPHROLOGY - ORIGINAL PAPER
Relationship of dietary and serum zinc and leptin levels with protein energy wasting in haemodialysis patients Gamze Yurtdaş1 · Efsun Karabudak2 · Fahri Mandıroğlu3 Received: 30 March 2020 / Accepted: 11 July 2020 © Springer Nature B.V. 2020
Abstract Objective This study was carried out to evaluate the relationship between dietary and serum zinc and leptin levels with protein-energy wasting (PEW) in haemodialysis patients. Methods The study was conducted on 80 volunteer patients aged 19–65 years who received haemodialysis treatment three times a week for at least 1 year. Anthropometric measurements and body composition analyses were performed. Blood samples were collected for serum zinc and leptin and other biochemical parameters. Food consumption of the patients was recorded for 3 days. Malnutrition-inflammation score (MIS) was calculated for all patients. PEW was assessed according to the criteria recommended by the International Society of Renal Nutrition and Metabolism (ISRNM). Results According to the ISRNM criteria, 38.1% of male patients and 36.8% of female patients were diagnosed with PEW. The median serum leptin levels of patients with PEW [9.0 (16.9) ng/mL] were significantly lower than those without PEW [20.7 (38.5) ng/mL] (p
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