Screening the Single Euploid Embryo Molecular Genetics in Reproducti

Intended for readers with a background in fertility medicine as well as those less familiar with IVF, this comprehensive work presents an update on preimplantation genetic testing to enable single embryo transfer (SET). An international cast of contributo

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Screening the Single Euploid Embryo Molecular Genetics in Reproductive Medicine

Screening the Single Euploid Embryo

E Scott Sills Editor

Screening the Single Euploid Embryo Molecular Genetics in Reproductive Medicine

Editor E Scott Sills Center for Advanced Genetics Reproductive Research Section Carlsbad, CA, USA Faculty of Science and Technology University of Westminster

London, UK

ISBN 978-3-319-16891-3 ISBN 978-3-319-16892-0 DOI 10.1007/978-3-319-16892-0

(eBook)

Library of Congress Control Number: 2015944096 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)

In Memoriam

Professor Robert P.S. Jansen (1946–2014) It is with great sadness that we acknowledge the passing of Professor Robert Jansen. Even while he was not well, Robert continued to guide and advise on research directions, with his contributions to this book being among his final writings. The impact of his scholarly work continues to have a global reach and will be felt for many years. Robert played a pivotal role in reproductive medicine and the development and progress of assisted conception in Australia over the last three decades. The founder and leader of Sydney IVF (now Genea), he led advances in clinical IVF application as well as the culture and incubation of human embryos. His contributions include the introduction of transvaginal ultrasound techniques in IVF, the development of MINC incubators and culture media which now enjoy global usage, PGD undertaken at the blastocyst stage, and many other groundbreaking developments. In an effort to improve pregnancy outcomes nearly 20 years ago, Robert used his own clinic as a research base to demonstrate that single embryo v

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In Memoriam

transfers were not only a feasibility but also a practical reality, and p