Sensitive Techniques for POCT Sensing on the Residues of Pesticides and Veterinary Drugs in Food

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FOCUSED REVIEW

Sensitive Techniques for POCT Sensing on the Residues of Pesticides and Veterinary Drugs in Food Lin Liu1,2,3 · Yueying Gao1,2,3 · Jinghan Liu1,2,3 · Ying Li1,2,3 · Ziye Yin1,2,3 · Yuanyuan Zhang1,2,3 · Fuwei Pi1,2,3 · Xiulan Sun1,2,3 Received: 24 February 2020 / Accepted: 24 October 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020

Abstract For the immense requirement on agriculture and animal husbandry, application of pesticides and veterinary drugs had become a normal state in the farming and ranching areas. However, to intently pursue the yields, large quantities of residues of pesticides and veterinary drugs have caused serious harm to both the environment and the food industry. To control and solve such an issue, a variety of novel techniques were developed in recent years. In this review, the development and features about point-of-care-testing (POCT) detection on the residues of pesticides and veterinary drugs, such as, electrochemistry (EC), enzyme-linked immunosorbent assay (ELISA) and nano-techniques, were systematically introduced. For each topic, we first interpreted the strategies and detailed account of such technical contributions on detection and assessment of the residues. Finally, the advantages and perspectives about mentioned techniques for ultrasensitive assessment and sensing on pesticides and veterinary drugs were summarized. Keywords  Pesticide · Veterinary drug · Residue · Detection methods

Introduction Nowadays, pesticides and veterinary drugs had been widely used in modern agriculture and animal husbandry. They effectively improved the quality and reduced yield loss through controlling weeds, pests as well as preventing diseases of plants and animals (Bartikova et al. 2016; Cooper and Dobson 2007; Lopes et al. 2012). For the maximum yields and economic benefits, there is a serious issue for

* Fuwei Pi [email protected] * Xiulan Sun [email protected] 1



State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, People’s Republic of China

2



National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, Jiangsu 214122, People’s Republic of China

3

Synergetic Innovation Center of Food Safety and Quality Control, Jiangnan University, Wuxi, Jiangsu 214122, People’s Republic of China



overuse of pesticides in China (Ding and Bao 2014; Zhang et al. 2015). For example, previous survey reported that the level of pesticides and veterinary drugs used per unit area of cropland in China is nearly 2.5 to 5 times the world average (Sun et al. 2019). Moreover, the investigations from official agent as illustrated in Fig. 1 clearly indicate that the total consumption of pesticides is becoming higher and higher in the world for pursuing the yields. Unfortunately, the investigations released by World Health Organization (WHO) had evidently confirmed that the long-term accumulation of residual pesticides and veterinary drugs in human body could i