Serum sphingosine-1-phosphate levels in bladder pain syndrome/interstitial cystitis patients: could it help in diagnosis
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ORIGINAL ARTICLE
Serum sphingosine‑1‑phosphate levels in bladder pain syndrome/ interstitial cystitis patients: could it help in diagnosis? Tariq Asi1 · Ahmet Asci1 · Mesut Altan1 · Ahmet Gudeloglu1 · Ali Ergen1 Received: 13 October 2019 / Accepted: 25 November 2019 © Springer-Verlag GmbH Germany, part of Springer Nature 2019
Abstract Purpose To find if there is any potential benefit of serum Sphingosine-1-Phosphate (S1P) level in the diagnosis of Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC). Methods and materials Patients newly or previously diagnosed with BPS/IC between September 2017 and December 2018 were included. Healthy individuals who volunteered to enter the study were included as control group. The measurements of serum S1P in both groups were compared. Multiple regression analysis was conducted to find out the significant factors affecting S1P results. Results A total of 47 BPS/IC patients and 47 healthy controls were included. BPS/IC patients were older than controls (48.5 ± 12.4 vs 38.9 ± 8.1 years, p
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