Synchronous double primary malignant tumor of the gallbladder and liver: a case report
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WORLD JOURNAL OF SURGICAL ONCOLOGY
CASE REPORT
Open Access
Synchronous double primary malignant tumor of the gallbladder and liver: a case report Ji Won Kim1, Jae Woong Han1, So Young Jung1, Jae Pil Jung1* and Jeong Won Kim2
Abstract We report a case of synchronous double primary tumor of gallbladder and liver. A 63-year-old male was admitted to the hospital complaining of abdominal discomfort. Enhanced computed tomography of the abdomen showed acute cholecystitis with tiny gallbladder stones and a 2.2 cm size enhanced nodule in the left lobe of the liver. Under the impression of acute cholecystitis with gall bladder stones and hepatocellular carcinoma of the left Liver, the patient underwent a laparotomy. At laparotomy, a mass was palpated on the surface of the neck portion of the gall bladder. Intraoperative frozen diagnosis revealed adenocarcinoma of the gall bladder. The patient was diagnosed as having gall bladder cancer and hepatocellular carcinoma, so extended cholecystectomy with dissection of regional lymph nodes and left hemihepatectomy were performed. Histological examination revealed moderated differentiated adenocarcinoma of gallbladder and hepatocellular carcinoma of liver. To our knowledge, the simultaneous occurrence of primary malignant tumor of the gallbladder and liver has never been published before. The patient is doing well with no evidence of recurrence 17 months after surgery. Keywords: Hepatocellular carcinoma, Gallbladder cancer, synchronous double primary malignant tumor
Background Synchronous double primary malignant neoplasms are a secondary malignancy occurring at the same time or within 6 months after the first malignancy. Improvement of survival rates for patients with malignancy due to early diagnosis and new treatments has enabled more patients to survive long enough to develop the subsequent primary malignancy, and development of more sophisticated diagnostic tools has made possible the detection of synchronous occult malignancies. Synchronous double primary malignant neoplasms in a single patient have been welldocumented in the literature. But, synchronous double primary malignant tumor of gallbladder and liver has never been reported. Herein, the authors report a case of a 63-year-old male patient with double primary cancer of gallbladder and liver. Case presentation In February 2010, a 63-year-old male patient visited our hospital with the chief complaint of abdominal discomfort * Correspondence: [email protected] 1 Department of Surgery, Kangnam Sacred Heart Hospital, Hallym Medical Center, 948-1, Daerim-1Dong, Yeongdeunpo-gu, Seoul 150-950, Korea Full list of author information is available at the end of the article
in right upper quadrant for 1 year. In 2008, the patient had been diagnosed with acute cholecystitis at our hospital. There was no remarkable family history. On admission, vital signs (blood pressure, heart rate, respiration rate, and body temperature) were within normal limits. The patient was in good general health and had no significant weight loss.
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