Toll-like Receptors: Roles in Infection and Neuropathology
Mammalian Toll-like receptors (TLRs) were first identified in 1997 based on their homology with Drosophila Toll, which mediates innate immunity in the fly. In recent years, the number of studies describing TLR expression and function in the nervous system
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Series Editors R. John Collier Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA Richard W. Compans Emory University School of Medicine, Department of Microbiology and Immunology, 3001 Rollins Research Center, Atlanta, GA 30322, USA Max D. Cooper Department of Pathology and Laboratory Medicine, Georgia Research Alliance, Emory University, 1462 Clifton Road, Atlanta, GA 30322, USA Yuri Y. Gleba ICON Genetics AG, Biozentrum Halle, Weinbergweg 22, Halle 6120, Germany Tasuku Honjo Department of Medical Chemistry, Kyoto University, Faculty of Medicine, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan Hilary Koprowski Thomas Jefferson University, Department of Cancer Biology, Biotechnology Foundation Laboratories, 1020 Locust Street, Suite M85 JAH, Philadelphia, PA 19107-6799, USA Bernard Malissen Centre d’Immunologie de Marseille-Luminy, Parc Scientifique de Luminy, Case 906, Marseille Cedex 9 13288, France Fritz Melchers Biozentrum, Department of Cell Biology, University of Basel, Klingelbergstr. 50–70, 4056 Basel Switzerland Michael B.A. Oldstone Department of Neuropharmacology, Division of Virology, The Scripps Research Institute, 10550 N. Torrey Pines, La Jolla, CA 92037, USA Sjur Olsnes Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Montebello 0310 Oslo, Norway Herbert W. “Skip” Virgin Washington University School of Medicine, Pathology and Immunology, University Box 8118, 660 South Euclid Avenue, Saint Louis, Missouri 63110, USA Peter K. Vogt The Scripps Research Institute, Dept. of Molecular & Exp. Medicine, Division of Oncovirology, 10550 N. Torrey Pines. BCC-239, La Jolla, CA 92037, USA
Current Topics in Microbiology and Immunology Previously published volumes Further volumes can be found at springer.com Vol. 311: Pulendran, Bali; Ahmed, Rafi (Eds.): From Innate Immunity to Immunological Memory. 2006. 13 figs. X, 177 pp. ISBN 3-540-32635-9
Vol. 323: Tracy, Steven; Oberste, M. Steven; Drescher, Kristen M. (Eds.): Group B Coxsackieviruses. 2008. ISBN 978-3-540-75545-6
Vol. 312: Boshoff, Chris; Weiss, Robin A. (Eds.): Kaposi Sarcoma Herpesvirus: New Perspectives. 2006. 29 figs. XVI, 330 pp. ISBN 3-540-34343-1
Vol. 324: Nomura, Tatsuji; Watanabe, Takeshi; Habu, Sonoko (Eds.): Humanized Mice. 2008. ISBN 978-3-540-75646-0
Vol. 313: Pandolfi, Pier P.; Vogt, Peter K.(Eds.): Acute Promyelocytic Leukemia. 2007. 16 figs. VIII, 273 pp. ISBN 3-540-34592-2
Vol. 325: Shenk, Thomas E.; Stinski, Mark F. (Eds.): Human Cytomegalovirus. 2008. ISBN 978-3-540-77348-1
Vol. 314: Moody, Branch D. (Ed.): T Cell Activation by CD1 and Lipid Antigens, 2007, 25 figs. VIII, 348 pp. ISBN 978-3-540-69510-3 Vol. 315: Childs, James, E.; Mackenzie, John S.; Richt, Jürgen A. (Eds.): Wildlife and Emerging Zoonotic Diseases: The Biology, Circumstances and Consequences of Cross-Species Transmission. 2007. 49 figs. VII, 524 pp. ISBN 978-3-540-70961-9 Vol. 316: Pitha, Paula M. (Ed.): Interferon: The 50th Anniversary. 2007. VII, 391 pp. ISBN 97
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