Viral Molecular Machines
A biological organism can be viewed as a collection of molecular machines well integrated to function as a self-replicating unit. One of the principal goals in biology is to be able to fully understand the mechanisms of an organism in atomic detail. Virus
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For further volumes: http://www.springer.com/series/5584
Michael G. Rossmann
●
Venigalla B. Rao
Editors
Viral Molecular Machines
Editors Michael G. Rossmann Department of Biological Sciences Purdue University West Lafayette, IN 47907-2032, USA [email protected]
Venigalla B. Rao Department of Biology The Catholic University of America Washington, DC 20064, USA [email protected]
ISSN 0065-2598 ISBN 978-1-4614-0979-3 e-ISBN 978-1-4614-0980-9 DOI 10.1007/978-1-4614-0980-9 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011941434 © Springer Science+Business Media, LLC 2012 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Acknowledgment
We thank Ms. Alice Kuaban for her assistance in the production of this book. We are grateful to all the authors who have freely given their time to make this book possible while having busy schedules to maintain their own research programs. Special thanks to our present and former lab members and collaborators for their contributions over the years. The research in our laboratories has been funded for many years by the National Science Foundation (MGR, MCB-0443899; VBR, MCB-0923873) and the National Institutes of Health (MGR and VBR, NIAID-R01AI081726).
Contents
1
Viruses: Sophisticated Biological Machines ................................................................... Michael G. Rossmann and Venigalla B. Rao
1
2
F1-ATPase: A Prototypical Rotary Molecular Motor .................................................... Kazuhiko Kinosita, Jr.
5
3
Principles of Virus Structural Organization .................................................................. B.V. Venkataram Prasad and Michael F. Schmid
17
4
Reconstructing Virus Structures from Nanometer to Near-Atomic Resolutions with Cryo-Electron Microscopy and Tomography.................................... Juan Chang, Xiangan Liu, Ryan H. Rochat, Matthew L. Baker, and Wah Chiu
Part I
49
Viral Entry Machines
5
Contractile Tail Machines of Bacteriophages ................................................................. Petr G. Leiman and Mikhail M. Shneider
93
6
Long Noncontractile Tail Machines of Bacteriophages ................................................. 115 Alan R. Davidson, Lia Cardarelli, Lisa G. Pell, Devon R.
