Recurrence of a functional adrenocortical oncocytoma of borderline malignant potential showing high FDG uptake on 18 F-F
- PDF / 1,143,323 Bytes
- 5 Pages / 595.276 x 790.866 pts Page_size
- 80 Downloads / 133 Views
CASE REPORT
Recurrence of a functional adrenocortical oncocytoma of borderline malignant potential showing high FDG uptake on 18F-FDG PET/CT Seung Hyun Son • Sang-Woo Lee • Bong-Il Song • Yun-Jin Jang • Ji-Young Park • Shin Young Jeong Byeong-Cheol Ahn • Jaetae Lee
•
Received: 20 May 2013 / Accepted: 14 August 2013 / Published online: 29 August 2013 Ó The Japanese Society of Nuclear Medicine 2013
Abstract Adrenocortical oncocytoma is a very rare tumor, which is not malignant and nonfunctioning in most cases. We report a case of a 53-year-old male with a 9.8 cm sized hyperfunctioning, well-encapsulated adrenal mass, which exhibited by high FDG uptake on a PET/CT scan. The patient had complained of symptoms of Cushing’s syndrome for 4 months. Laparoscopic adrenalectomy was performed and the mass was pathologically confirmed as adrenocortical oncocytoma of uncertain malignant potential. Four years after surgery, the tumor recurred with distant metastases, which was proven by subsequent biopsy. 18F-FDG PET/CT also showed hypermetabolism in the recurred tumor and multiple metastatic lesions. Adrenocortical oncocytoma of borderline malignant potential with high FDG uptake may require long-term follow-up with clinical, hormonal, and imaging evaluations. Keywords Adrenocortical oncocytoma PET/CT Recurrence
18
F-FDG
Introduction Oncocytic tumors or tumors with oncocytic features are characterized histologically by cells with eosinophilic granular cytoplasm, and ultrastructurally by the presence of numerous closely packed mitochondria [1]. Oncocytic tumors are uncommon neoplasms that occur most frequently in the salivary glands, kidney, thyroid, parathyroid, and pituitary. However, adrenocortical oncocytomas are rare [2]. In fact, only about 110 cases of the adrenocortical oncocytoma have been reported in the literature [3]. Although oncocytomas have been traditionally considered nonfunctional and benign, about 20 % of adrenocortical oncocytomas demonstrate elements of malignancy and 25–30 % of these appear to be associated with the hypersecretion of adrenal hormones. Here, we present the clinicopathologic and imaging findings of a case of functional adrenocortical oncocytoma of borderline malignant potential, which finally recurred with multiple metastasis 4 years after surgical resection.
Case report S. H. Son S.-W. Lee (&) B.-I. Song S. Y. Jeong B.-C. Ahn J. Lee Department of Nuclear Medicine, Kyungpook National University School of Medicine and Hospital, 807 Hogukno, Buk-gu, Daegu 702-210, Republic of Korea e-mail: [email protected] Y.-J. Jang Department of Radiology, Kyungpook National University School of Medicine and Hospital, Daegu, South Korea J.-Y. Park Department of Pathology, Kyungpook National University School of Medicine and Hospital, Daegu, South Korea
A 53-year-old male presented at our out-patient department with histories of hypertension for 6 months, 2 kg weight gain with progressive puffy face and dyspnea for 3 months. And, he also got progressive swelling of both calves for 1 month.
Data Loading...
