Skeletal Muscle Plasticity in Health and Disease

The ability of striated muscle tissue to adapt to changes in activity or in working conditions is extremely high. In some ways it is comparable to the ability of the brain to learn. The interest in muscle adaptation is increasing in relation to the idea t

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Edited by Roberto Bottinelli and Carlo Reggiani The ability of striated muscle tissue to adapt to changes in activity or in working conditions is extremely high. In some ways it is comparable to the ability of the brain to learn. The interest in muscle adaptation is increasing in relation to the idea that physical fitness helps in the prevention of disease, may counteract the loss of physical performance and generally improves wellbeing. Plasticity is the word used since the late 1970’s to indicate collectively all the processes and mechanisms which form the background of muscle adaptation. This book aims to provide a systematic updating of the available knowledge on molecular and cellular mechanisms, as well as on changes at whole muscle level. The book wishes to be a guide and a help for people who enter the field as PhD or as medical students, but is also a tool for refreshing and updating knowledge for people already active in the field in basic sciences as well as in applied disciplines such as neurology, sports science and rehabilitation..

Skeletal Muscle Plasticity in Health and Disease: From Genes to Whole Muscle

Skeletal Muscle Plasticity in Health and Disease: From Genes to Whole Muscle

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A D VA N C E S I N M U S C L E R E S E A R C H

Skeletal Muscle Plasticity in Health and Disease: From Genes to Whole Muscle Edited by Roberto Bottinelli and Carlo Reggiani

Roberto Bottinelli and Carlo Reggiani (Eds.)

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Series Editor: G.J.M. Stienen

SKELETAL MUSCLE PLASTICITY IN HEALTH AND DISEASE

Advances in Muscle Research Volume 2

Series Editor G.J.M. Stienen, Vrije Universiteit, Amsterdam, The Netherlands

Skeletal Muscle Plasticity in Health and Disease From Genes to Whole Muscle Edited by

Roberto Bottinelli University of Pavia, Pavia, Italy

and

Carlo Reggiani University of Padova, Padova, Italy

A C.I.P. Catalogue record for this book is available from the Library of Congress.

ISBN-10 ISBN-13 ISBN-10 ISBN-13

1-4020-5176-X (HB) 978-1-4020-5176-0 (HB) 1-4020-5177-8 (e-book) 978-1-4020-5177-7 (e-book) Published by Springer, P.O. Box 17, 3300 AA Dordrecht, The Netherlands.

Printed on acid-free paper

All Rights Reserved © 2006 Springer No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work.

CONTENTS

Preface

vii

1. Skeletal Muscle Plasticity – History, Facts and Concepts Dirk Pette 2. Large Scale Gene Expression Profiles as Tools to Study Skeletal Muscle Adaptation Susan C. Kandarian 3. Striated Muscle Plasticity: Regulation of the Myosin Heavy Chain Genes Fadia Haddad, Clay E. Pandorf, Julia M. Giger and Kenneth M. Baldwin 4. Signaling Pathways Controlling Muscle Fiber Size and Type in Res