Stem Cell Microenvironments and Beyond

This book discusses the main stem cell niches under distinct pathophysiological conditions. The role of tissue microenvironments in stem cell regulation, as well as modern methodologies and new techniques for the identification and characterization of ste

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Alexander Birbrair Editor

Stem Cell Microenvironments and Beyond

Advances in Experimental Medicine and Biology Volume 1041 Series Editors IRUN R. COHEN, Weizmann Institute Science, Rehovot, Israel ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research, Orangeburg, New York, USA JOHN D. LAMBRIS, University of Pennsylvania, Philadelphia, Pennsylvania, USA RODOLFO PAOLETTI, University of Milan, Milan, Italy NIMA REZAEI, Tehran University of Medical Sciences, Tehran, Iran

More information about this series at http://www.springer.com/series/5584

Alexander Birbrair Editor

Stem Cell Microenvironments and Beyond

Editor Alexander Birbrair Department of Pathology Federal University of Minas Gerais Belo Horizonte, MG, Brazil

ISSN 0065-2598     ISSN 2214-8019 (electronic) Advances in Experimental Medicine and Biology ISBN 978-3-319-69193-0    ISBN 978-3-319-69194-7 (eBook) DOI 10.1007/978-3-319-69194-7 Library of Congress Control Number: 2017959608 © Springer International Publishing AG 2017 Chapter 10 is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/). For further details see license information in the chapter. This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

This book Stem Cell Microenvironments and Beyond presents contributions by expert researchers and clinicians in the multidisciplinary areas of medical and biological research. The chapters provide timely detailed overviews of recent advances in the field. The texts are about stem cell microenvironments in different tissues and under distinct pathophysiological conditions. The authors focus on