The Application of Molecular Techniques on Bone Marrow Trephines
Examination of the bone marrow (BM) is a standard diagnostic procedure for the evaluation of patients with malignant lymphoma. Aspiration cytology, flow cytometric immunophenotyping, and the histopathological and immunohistochemical examination of BM biop
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Dimitra Anagnostou • Estella Matutes Editors
Bone Marrow Lymphoid Infiltrates Diagnosis and Clinical Impact
Editors Dimitra Anagnostou, M.D. Department of Haematopathology Referral Centre Evangelismos Hospital Athens Greece
Estella Matutes, M.D., Ph.D., FRCPath Department of Haemato-Oncology Royal Marsden Hospital London United Kingdom
ISBN 978-1-4471-4173-0 ISBN 978-1-4471-4174-7 DOI 10.1007/978-1-4471-4174-7 Springer Dordrecht Heidelberg New York London
(eBook)
Library of Congress Control Number: 2012945533 © Springer-Verlag London 2012 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Foreword
It is an honor and pleasure for me to write an introduction to this book on lymphoid infiltrates in the bone marrow. Historically seen, it is the result of a cooperation of hematopathologists whose interest in bone marrow led to the founding of the European Bone Marrow Working Group in 1992. What began as a group of ten persons is now, 20 years later, a blooming society of more than 150 members. Annual educational meetings attract over 300 participants, showing the need for a better understanding of bone marrow morphogy. The book that is now in your hands is the fruit of discussions and presentations on this topic in the last two decennia and one of the scientific
