Topics in Fluorescence Spectroscopy Probe Design and Chemical Sensin

Time-resolved fluorescence spectroscopy is widely used as a research tool in bioch- istry and biophysics. These uses of fluorescence have resulted in extensive knowledge of the structure and dynamics of biological macromolecules. This information has been

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Topics in Fluorescence Spectroscopy Edited by JOSEPH R. LAKOWICZ Volume Volume Volume Volume

1: Techniques 2: Principles 3: Biochemical Applications 4: Probe Design and Chemical Sensing

Topics in Fluorescence Spectroscopy Volume 4 Probe Design and Chemical Sensing

Edited by

JOSEPH R. LAKOWICZ Center for Fluorescence Spectroscopy and Department of Biological Chemistry University of Maryland School of Medicine Baltimore, Maryland

KLUWER ACADEMIC PUBLISHERS NEW YORK, BOSTON, DORDRECHT, LONDON, MOSCOW

eBook ISBN: Print ISBN:

0-306-47060-8 0-306-44784-3

©2002 Kluwer Academic Publishers New York, Boston, Dordrecht, London, Moscow Print ©1994 Kluwer Academic/Plenum Publishers New York All rights reserved

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Contributors

J. Ricardo Alcala • Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106 Shabbir B. Bambot • Department of Chemical and Biochemical Engineering, University of Maryland Baltimore County, Baltimore, Maryland 21228; and Medical Biotechnology Center of the Maryland Biotechnology Institute, University of Maryland at Baltimore, Baltimore, Maryland 21201 David J. S. Birch • Department of Physics and Applied Physics, University of Strathclyde, Glasgow G4 0NG, Scotland, United Kingdom Gary Carter • Department of Electrical Engineering, University of Maryland Baltimore County, Baltimore, Maryland 21228 Guillermo A. Casay • Georgia 30303

Department of Chemistry, Georgia State University, Atlanta,

Anthony W. Czarnik • Department of Chemistry, Ohio State University, Columbus, Ohio 43210 B. A. DeGraff • Department of Chemistry, James Madison University, Harrisonburg, Virginia 22807 J. N. Demas • Department of Chemistry and Biophysics, University of Virginia, Charlottesville, Virginia 22908 K. T, V Grattan • Department of Physics, Measurement and Instrumentation Centre, School of Electrical Engineering and Applied Physics, City University, London EC1 V0HB, United Kingdom Raja Holavanahali • Department of Electrical Engineering, University of Maryland Baltimore County, Baltimore, Maryland 21228 Graham Hungerford • Department of Physics and Applied Physics, University of Strathclyde, Glasgow G4 0NG, Scotland, United Kingdom v

vi

Contributors

Simon C. W. Kwong • Department of Chemical and Biochemical Engineering, University of Maryland Baltimore County, Baltimore, Maryland 21228; and Medical Biotechnology Center of the Maryland Biotechnology Institute, University of Maryland at Baltimore, Baltimore, Maryland 21201 Joseph R. Lakowicz • Center for Fluorescence Spectroscopy and Department of Biological Chemistry, University of Maryland School of Medicine, Baltimore, Maryland 21201 René Lapouyade • Photophysique et Photochimie Moléculaire, URA (CNRS)