Valine acts as a nutritional signal in brain to activate TORC1 and attenuate postprandial ammonia-N excretion in Chinese

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Valine acts as a nutritional signal in brain to activate TORC1 and attenuate postprandial ammonia-N excretion in Chinese perch (Siniperca chuatsi) Jie Wang & Xu-Fang Liang & Shan He & Yan-Peng Zhang & Jiao Li & Kang Huang & Lin-Jie Shi & Ping Ren Received: 28 June 2019 / Accepted: 13 January 2020 # Springer Nature B.V. 2020

Abstract An emerging concept is that the hypothalamic nutrient sensor can regulate peripheral energy metabolism via a brain-liver circuit. Valine is an essential branched-chain amino acid (BCAA) that drives J. Wang : X.