A Review on Green Synthesis of Zinc Oxide Nanoparticles Using Plant Extracts and Its Biomedical Applications
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A Review on Green Synthesis of Zinc Oxide Nanoparticles Using Plant Extracts and Its Biomedical Applications Sunday Adewale Akintelu 1,2
&
Aderonke Similoluwa Folorunso 3
# Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Zinc oxide nanoparticles (ZnO NPs) are one of the prominent metal oxide nanoparticles with significant applications in many industries and research institutes. Various methods of synthesis have been adopted in the production of ZnO NPs so as to meet its high demand. The environmental implications and economic challenges attached to most of the means of ZnO NPs synthesis have resulted in the quest for other alternatives with environmental and economic benefits. Interestingly, the biological method of synthesis using plant sources have been found appropriate for the production of ZnO NPs dues to its numerous health, environmental, economic, and medicinal benefits. The distinctive features of ZnO NPs synthesized using plant extracts enhanced its application in agriculture for the production of fertilizers, pesticides, and fumigants. In the field of medicine and pharmacy, phytosynthesized ZnO NPs have gained remarkable usage in the production of disinfectant, antifungal, anticancer, antioxidant, anti-inflammatory and antidiabetics agents. Despite the enlisted benefits of biosynthesized ZnO NPs, the difficulties associated with the elucidation of formation mechanism and reactions still remain unraveled. This review described the summary of the recent advances in the synthesis, mechanism routes, characterization techniques, and applications of biosynthesized ZnO NPS in agriculture, medicine, and textile industries. Keywords Green synthesis . Zinc oxide . Nanoparticles . Plant extracts and biomedical applications
1 Introduction Metal and metal oxide nanoparticles have shown wide applications in numerous fields such as agriculture, pharmacy, catalysis, medicine, textile, heavy industry dealing with consumer goods, and antimicrobial assay [1–5]. In particular, ZnO NPs applications in coating, antimicrobial therapy, cosmetics, medicinal purpose, photocatalysis, pesticides, sunscreen materials, agriculture, and antimicrobial agent are remarkable [6, 7]. The excellent antimicrobial potentials of ZnO NPs have aided its several applications in surgical tapes antiseptic creams, shampoos, and calamine lotions. ZnO NPs has been
* Sunday Adewale Akintelu [email protected] 1
School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, China
2
Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, Nigeria
3
Department of Chemistry, Louisiana State University, Baton Rouge, LA, USA
reported to demonstrate broad spectrum against bacterial growth at low concentration [8]. ZnO NPs earn its remarkable antimicrobial application and biosafety features in medicinal applications having been approved by the United State Food and Drug Administration (21, CFR 182, 8991). The use of ZnO NPs in electronics, rubber
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