Vitex negundo assisted green synthesis of metallic nanoparticles with different applications: a mini review

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(2020) 6:90

Future Journal of Pharmaceutical Sciences

REVIEW

Open Access

Vitex negundo assisted green synthesis of metallic nanoparticles with different applications: a mini review Shriniwas P. Patil1*

and Subhash T. Kumbhar2

Abstract Background: Several attempts have been made for green synthesis of nanoparticles of different metals and metal oxides, revealing the significance of plant extracts in reducing metal source to nanoparticles and applications in various scientific domains. Main body: The present article focus on applications of Vitex negundo leaves extract in fabrication of nanoparticles of various metals like silver, gold, zinc oxide, and copper oxide. Vitex negundo is evergreen, perennial shrub, belonging to family Verbenaceae. Its leaves are reported to contain several phytochemicals like iridoids, flavonoids, and their glycosides, terpenoids. In respective research attempts, these metallic nanoparticles were evaluated for one or more applications like anti-microbial activity and/or photocatalytic activity. Conclusions: Use of V. negundo polar extract indicated involvement of its polar phytocompounds in reducing the metal source and stabilizing the nanoparticles. In conclusion, it could be noted that metal nanoparticles have better antimicrobial activity and photocatalytic potential over aqueous leaves extract.

Background Since few decades, many research groups are working hard for the development of simple and facile methods for the synthesis of metallic nanoparticles. The reason lies in their applications in various scientific domains. Applications so explored can be classified into two types. Biological applications include applications of nanoparticles explored for their anti-bacterial [1], anti-fungal [2], anti-viral [3], antiinflammatory [4], anti-cancer [5, 6], anti-diabetic [7], and anti-oxidant potentials [8]. Non-biological applications include photocatalysis of pollutant dyes like methylene blue, reduction of 4-nitrophenol and its derivatives used in pesticides [9], use in dye-sensitized solar cells (DSSCs) [10]. Using C. gigantea latex, yttrium nitrate, europium nitrate, sodium chloride, and water, Ramakrishna et al. synthesized Eu3+ doped Y2SiO5 nanophosphors; those can be used in * Correspondence: [email protected] 1 Department of Pharmacognosy, SCES’s Indira College of Pharmacy, Pune, India Full list of author information is available at the end of the article

light-emitting diodes (LEDs) [11]. Recently, Wang et al. modified zinc oxide nanoparticles using uniformly dispersed silver nanoparticles and found enhancement in ethanol fumes and H2S gas sensing performance [12]. For synthesis of metallic nanoparticles, several biological systems have been tried. Shivaji et al. employed cell-free culture supernatants of psychrophilic bacteria Pseudomonas proteolytica, Pseudomonas antarctica, Pseudomonas meridiana, Arthrobacter gangotriensis, Arthrobacter kerguelensis, Bacillus cecembensis, and Bacillus indicus [13], while Ahmed et al. used F. oxysporum to reduce silver oxide for prepa