Ciprofloxacin
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Ciprofloxacin Linear IgA bullous dermatosis in a child: case report An 11-year-old boy developed linear IgA bullous dermatosis following treatment with ciprofloxacin. The boy presented to an emergency department with a complaint of unresolved rash. Three months earlier, he was diagnosed with streptococcal pharyngitis and had received ciprofloxacin [dosage and route not stated]. After treatment day 5, he had developed a nonpruritic papular rash limited to his torso. Before presentation to the emergency department, the boy’s mother had treated the rash with an over-the-counter topical agent, which resulted in darkening of the papules. Following this, he was prescribed amoxicillin/clavulanic acid and aciclovir for herpes zoster infection. On presentation, his rash had spread to his torso and bilateral upper extremities, and was nonblanching and present in a collarette formation with negative Nikolsky’s sign. Some bullae were present with clear discharge. Linear IgA bullous dermatosis was suspected. He started receiving oral erythromycin, topical mometasone, and petroleum jelly and mupirocin ointment. At a follow-up 6 days later, his symptoms were resolving and erythromycin was stopped. Linear IgA bullous dermatosis was confirmed by a punch biopsy. His lesions flared up again 19 days and 3 months later and were treated with oral erythromycin. Auerbach JS, et al. Ciprofloxacin-induced immunoglobulin A disease. American Journal of Emergency Medicine 28: 641.e1-641.e3, No. 5, Jun 2010. Available 803029920 from: URL: http://dx.doi.org/10.1016/j.ajem.2009.08.026 - USA
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Reactions 7 Aug 2010 No. 1313
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