Ciprofloxacin
- PDF / 183,603 Bytes
- 1 Pages / 595.245 x 841.846 pts (A4) Page_size
- 35 Downloads / 190 Views
1
★S
First report of rectal malakoplakia in an elderly patient: case report A 70-year-old woman with chronic bronchiectasis presented with vomiting, diarrhoea, abdominal pain and diaphoresis. Two weeks previously, she had received ciprofloxacin [dosage, route and duration of treatment to reaction onset not stated] for a pulmonary Proteus mirabilis superinfection. Empirical IV metronidazole was started due to a suspicion of pseudomembranous colitis. Initial rectosigmoidoscopy showed oedema with purplish areas and a whitish membrane that nearly covered the entire mucosal surface. Biopsy findings were consistent with an ulcerative or pseudomembranous background. A repeat rectoscopy and biopsy 1 week later led to a histologic diagnosis of malakoplakia. She received antibiotics and her condition gradually improved over the following weeks. Amat Villegas I, et al. Rectal malacoplakia associated with colitis after antibiotic therapy: Apropos of a case. Gastroenterologia y Hepatologia 33: 683-684, No. 9, Nov 2010. Available from: URL: http://dx.doi.org/10.1016/j.gastrohep.2010.03.003 803048176 [Spanish; summarised from a translation] - Spain
»
Editorial comment: A search of AdisBase, Medline and Embase did not reveal any previous case reports of malakoplakia associated with ciprofloxacin. The WHO ADR database did not contain any previous case reports of malacoplakia gastrointestinal associated with ciprofloxacin.
0114-9954/10/1335-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved
Reactions 22 Jan 2011 No. 1335
Data Loading...
