Docetaxel
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Docetaxel Alcoholic intoxication due to alcohol excipient: case report A 44-year-old man, who had a history of alcohol dependence, received IV docetaxel 75 mg/m2 [frequency not stated] and prednisolone for metastatic prostate cancer. At his ninth cycle of chemotherapy, he received a new docetaxel formulation, containing 50% alcohol. During his infusion, he began experiencing symptoms of alcoholic intoxication, including drowsiness, confusion, imbalance and blurred vision with diplopia. The infusion was stopped; however, his dizziness persisted for at least 3 hours. In his final cycle of treatment, he was switched back to his previous docetaxel formulation and had no recurrence of symptoms. Mirza A, et al. Alcohol intoxication with the new formulation of docetaxel. Clinical Oncology 23: 560-561, No. 8, Oct 2011. Available from: URL: http:// 803062090 dx.doi.org/10.1016/j.clon.2011.04.010 - United Kingdom
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Reactions 29 Oct 2011 No. 1375
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