Docetaxel
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Oesophageal fistula and pneumonia: 3 case reports
In a retrospective study of elderly patients aged ≥ 76 years treated between January 2009 and May 2018, 3 patients [sexes and exact ages not stated] were described, who developed oesophageal fistula or pneumonia during treatment with docetaxel for oesophageal squamous cell carcinoma [routes, durations of treatment to reactions onsets and outcomes not stated]. The patients, who were diagnosed with oesophageal squamous cell carcinoma, started receiving radiotherapy 5 days per week for a total dose of 60Gy along with concurrent chemotherapy including docetaxel 10 mg/m2 weekly for 6 consecutive weeks. Subsequently, one of the two patients developed pneumonia (n=1), and the remaining two patients developed oesophageal fistula. Consequently, the patient’s radiotherapy with docetaxel were discontinued. Kawamoto T, et al. Clinical impact of baseline renal function on the safety of radiotherapy with concurrent docetaxel for esophageal cancer in elderly patients. Esophagus 17: 803517284 425-432, No. 4, Oct 2020. Available from: URL: http://doi.org/10.1007/s10388-020-00731-y
0114-9954/20/1832-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved
Reactions 28 Nov 2020 No. 1832
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