Effects of Ionic Liquid and Liposomes on the Structure, Stability, and Function of Nucleic Acids
The influences of homogenous molecular crowding on the structures and thermodynamics of various nucleic acid sequences in aqueous solution have been reported. Little is known, however, about the behaviors of nucleic acids in heterogeneous conditions such
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Volker A. Erdmann Wojciech T. Markiewicz Jan Barciszewski Editors
Chemical Biology of Nucleic Acids Fundamentals and Clinical Applications
RNA Technologies
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Volker A. Erdmann • Wojciech T. Markiewicz • Jan Barciszewski Editors
Chemical Biology of Nucleic Acids Fundamentals and Clinical Applications
Editors Volker A. Erdmann Institute of Chemistry/Biochemistry Free University Berlin Berlin, Germany
Wojciech T. Markiewicz Jan Barciszewski Institute of Bioorganic Chemistry Polish Academy of Sciences Poznan, Poland
ISBN 978-3-642-54451-4 ISBN 978-3-642-54452-1 (eBook) DOI 10.1007/978-3-642-54452-1 Springer Heidelberg New York Dordrecht London Library of Congress Control Number: 2014937792 © Springer-Verlag Berlin Heidelberg 2014 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
This year the RNA technologies are celebrating two very important anniversaries. The first one is the 60th anniversary of the founding of the RNA Tie Club and the other one is the 40th anniversary of the successful crystallization and structural determination of the phenylalanine-specific tRNA from yeast. The 60th anniversary of the RNA Tie Club is indeed a very important date to remember! The 20
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