Quadruplex Nucleic Acids
Gaining Insights into the Small Molecule Targeting of the G-Quadruplex in the c-MYC Promoter Using NMR and an Allele-Specific Transcriptional Assay, by Christine E. Kaiser, Vijay Gokhale, Danzhou Yang and Laurence H. Hurley.- Higher-Order Quadruplex Struc
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Topics in Current Chemistry
Editorial Board: K.N. Houk, Los Angeles, CA, USA C.A. Hunter, Sheffield, UK M.J. Krische, Austin, TX, USA J.-M. Lehn, Strasbourg, France S.V. Ley, Cambridge, UK M. Olivucci, Siena, Italy J. Thiem, Hamburg, Germany M. Venturi, Bologna, Italy P. Vogel, Lausanne, Switzerland C.-H. Wong, Taipei, Taiwan H.N.C. Wong, Shatin, Hong Kong H. Yamamoto, Chicago, IL, USA
For further volumes: http://www.springer.com/series/128
Aims and Scope The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage includes all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether at the university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented. A description of the laboratory procedures involved is often useful to the reader. The coverage should not be exhaustive in data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Discussion of possible future research directions in the area is welcome. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students.
Jonathan B. Chaires David Graves l
Editors
Quadruplex Nucleic Acids
With contributions by R. Buscaglia J.B. Chaires W.L. Dean A. De Cian V. Do¨tsch S. Foldynova´-Trantı´rkova´ T. Fujimoto C. Giancola V. Gokhale A. Granzhan J. Gros F. Hamon R. Ha¨nsel L.H. Hurley C.E. Kaiser E. Largy H.T. Le J.-L. Mergny D. Miyoshi R. Moriyama B. Pagano L. Petraccone A. Randazzo G.P. Spada N. Sugimoto M.-P. Teulade-Fichou P.L.T. Tran L. Trantı´rek J.O. Trent D. Verga M. Webba da Silva D. Yang
Editors Jonathan B. Chaires James Graham Brown Cancer Center University of Louisville Louisville, KY USA
David Graves Department of Chemistry University of Alamaba at Birmingham Birmingham, Alaska USA
ISSN 0340-1022 ISSN 1436-5049 (electronic) ISBN 978-3-642-34742-9 ISBN 978-3-642-34743-6 (eBook) DOI 10.1007/978-3-642-34743-6 Springer Heidelberg New York Dordrecht London Library of Congress Control Number: 2012954486 # Springer-Verlag Berlin Heidelberg 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storag
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