Nucleic Acids and Molecular Biology
A wide range of topics are covered, including articles on nucleic acid structure, through their interactions with proteins to the control of gene expression. A number of authors address the subject of RNA, including the difficult but important subject of
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Professor Dr. FRITz ECKSTEIN Max-Planck-Institut fUr experimentelle Medizin Abteilung Chemie Hermann-Rein-StraBe 3 3400 Ol>ttingen, FRO Dr. DAVID M.J. LILLEY University of Dundee Biochemistry Department Dundee DDI 4HN, UK
Cover illustration by kind permission ofB.W. Mlltthews
ISBN-13:978-3-642-83711-1 e-ISBN-13:978-3-642-83709-8 DOl: 10.1007/978-3-642-83709-8 'This work is subject to copyright. All rights are reserved, whether the whole or part of the matenal is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks. Duplication of this publication or parts thereof is only permitted under the provisions of the German Copyright Law of September 9, 1965, in its version of June 24, 1985, and a copyright fee must always be paid. Violations fall under the prosecution act of the German Copyright Law. @ Springer-Verlag Berlin Heidelberg 1989 Softcover reprint of the hardcover 1st edition 1989
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Preface to the Series
From its inception, molecular biology has always been a discipline of rapid development. Despite this, we are presently experiencing a period of unprecedented proliferation of information in nucleic acid studies and molecular biology. These areas are intimately interwoven, so that each influences the other to their mutual benefit. This rapid growth in information leads to ever-increasing specialization, so that it becomes increasingly difficult for a scientist to keep abreast of developments in all the various aspects of the field, although an upto-date knowledge of the field as a whole is highly desirable. With this background in mind, we have conceived the present series Nucleic Acids and Molecular Biology. It comprises focused review articles by active researchers, who report on the newest developments in their areas of particular interest. The reviews are not intended to be exhaustive, but rather to place the most recent data into context. This format will allow our colleagues of familiarize themselves with new developments in areas outside their own immediate speciality, thus facilitating a more global view of their own work. Moreover, we hope sincerely that this will convey some of the excitement of the interdisciplinary nature of the study of nucleic acids and molecular biology. This series is planned to appear annUally. This period will allow us to return to important topics with sufficient frequency to cover new developments as they emerge. FRITZ ECKSTEIN DAVID MJ. LILLEY
Introduction to Volume 3
The third volume of Nucleic Acids and Molecular Biology contains articles ranging from nucleic acid st
