Ferroptosis in Health and Disease
This book sheds new light on ferroptosis, as an only recently recognised form of regulated cell death. Its respective chapters address the numerous implications that ferroptosis can have for virtually all aspects of metabolism. They also share insights on
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Ferroptosis in Health and Disease
Ferroptosis in Health and Disease
Daolin Tang Editor
Ferroptosis in Health and Disease
Editor Daolin Tang Department of Surgery UT Southwestern Medical Center Dallas, Texas, USA
ISBN 978-3-030-26779-7 ISBN 978-3-030-26780-3 https://doi.org/10.1007/978-3-030-26780-3
(eBook)
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Contents
1
Lipid Metabolism and Ferroptosis . . . . . . . . . . . . . . . . . . . . . . . . . . Amy Tarangelo and Scott J. Dixon
1
2
Iron Metabolism and Ferroptosis . . . . . . . . . . . . . . . . . . . . . . . . . . Shinya Toyokuni and Izumi Yanatori
27
3
Regulation and Function of Autophagy During Ferroptosis . . . . . . Daolin Tang and Rui Kang
43
4
Heat Shock Proteins: Endogenous Modulators of Ferroptosis . . . . . Rui Kang and Daolin Tang
61
5
Biological Aspects of Endoplasmic Reticulum Stress in Ferroptosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Young-Sun Lee and Yong J. Lee
83
6
Gpx4 and Ferroptosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Qitao Ran and Paulina Mozolewska
99
7
ACSL4 as the First Reliable Biomarker of Ferroptosis Under Pathophysiological Conditions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111 Caroline Moerke, Franziska Theilig, Ulrich Kunzendorf, and Stefan Krautwald
8
Regulation of Ferroptosis by MicroRNAs . . . . . . . . . . . . . . . . . . . . 125 Yongfei Yang
9
Ferroptosis in Cardiovascular Disease . . . . . . . . . . . . . . . . . . . . . . . 147 Jason K. Higa, Nicholas K. Kawasaki, and Takashi Matsui
10
Ferroptosis in Nervous System Diseases . . . . . . . .
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