Hepatitis C virus genotypes in Saudi Arabia: a future prediction and laboratory profile
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RESEARCH
Open Access
Hepatitis C virus genotypes in Saudi Arabia: a future prediction and laboratory profile Amen Bawazir1*, Fahad AlGusheri2, Hoda Jradi1, Mohammed AlBalwi3 and Abdel-Galil Abdel-Gader4
Abstract Background: Hepatitis C virus (HCV) genotypes and subtypes are considered an important tool for epidemiological and clinical studies and valuable markers for disease progression and response to antiviral therapy. The aim of this study was to identify the prevalence of HCV genotypes and their relation to socio-demographic factors particularly age and sex, various biochemical profiles and viral load. Methods: The records (630) of Saudi patients positive for HCV (2007–2011) reported in the system of the Molecular Pathology Laboratory at a tertiary reference hospital in Riyadh, Saudi Arabia were analyzed. Socio-demographic characteristics, liver biochemical profile, viral load and co-infection with HBV and HIV were retrieved from the hospital database. The associations of continuous and categorical variables with genotypes were analyzed. Result: The overall mean age of the surveyed patients was 59 years ±0.5 years (21% were
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