Methods in Biobanking
International biobank collaborations allow for studies with large number of subjects where generalizability of findings across populations can be investigated, which means establishing quality criteria concerning the nature of the sample, conditions of sa
- PDF / 10,022,036 Bytes
- 418 Pages / 504 x 720 pts Page_size
- 60 Downloads / 195 Views
in
Molecular Biology™
Series Editor John M. Walker School of Life Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For other titles published in this series, go to www.springer.com/series/7651
Methods in Biobanking Edited by
Joakim Dillner Bio Banking and Molecular Resource, Infrastructure of Sweden (BBMRI.se), Karolinska Institutet, Stockholm, Sweden
Editor Joakim Dillner Bio Banking and Molecular Resource Infrastructure of Sweden (BBMRI.se) Karolinska Institutet Stockholm, Sweden
ISSN 1064-3745 e-ISSN 1940-6029 ISBN 978-1-58829-995-6 e-ISBN 978-1-59745-423-0 DOI 10.1007/978-1-59745-423-0 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2010938369 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Humana Press, c/o Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface Recent technological advances, primarily in molecular biology and genetics, have greatly improved our ability to investigate how interactions between genes and environment affect our health. Access to reliable information concerning family members, health, and life-style factors that can be linked to biological samples from large numbers of individuals creates an enormous new potential in this area. Although biobanks can be used to study conventional risk markers (such as cholesterol levels and cardiovascular risk), a major emphasis is being placed on the potential for genetic studies. Current studies frequently demonstrate that the importance of genes becomes most evident under circumstances determined by life-style factors. For example, the importance of serum cholesterol for cardiovascular risk can be viewed in a context of genetic variation of lipoprotein genes, receptors, and diet. Modern biobanks are systematically built to allow comprehensive recruitment of cases and matched controls from the same background population and social strata. At the same time, internati
Data Loading...
