Multipotent Stem Cells of the Hair Follicle Methods and Protocols
This volume discusses methods for the study of multipotent and pluripotent stem cells of the hair follicle. The stem cells described are involved in both the growth of the hair follicle and its production of the hair shaft, as well as the growth of the ha
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Robert M. Hoffman Editor
Multipotent Stem Cells of the Hair Follicle Methods and Protocols
METHODS
IN
MOLECULAR BIOLOGY
Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Multipotent Stem Cells of the Hair Follicle Methods and Protocols
Edited by
Robert M. Hoffman AntiCancer, Inc., San Diego, CA, USA; University of California, San Diego, CA, USA
Editor Robert M. Hoffman AntiCancer, Inc. San Diego, CA, USA University of California San Diego, CA, USA
ISSN 1064-3745 ISSN 1940-6029 (electronic) Methods in Molecular Biology ISBN 978-1-4939-3784-4 ISBN 978-1-4939-3786-8 (eBook) DOI 10.1007/978-1-4939-3786-8 Library of Congress Control Number: 2016938078 © Springer Science+Business Media New York 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer Science+Business Media LLC New York
Preface This volume describes methods for the study of multipotent and pluripotent stem cells of the hair follicle. The stem cells described are involved in both the growth of the hair follicle and its production of the hair shaft, as well as in growth of the hair follicle sensory nerve. Also described in this volume are very unexpected results accumulated in the first 15 years of the present century demonstrating a set of hair follicle-associated pluripotent (HAP) stem cells which not only have the capability for regenerating the hair follicle sensory nerve, but also can differentiate ex vivo and in vivo to multiple cell types not associated with the hair follicle, including glial cells, motor neurons, and beating cardiac muscle cells. The potential for HAP stem cells for regenerative medicine is also described in detail. San Diego, CA, USA
Robert M. Hoffman
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Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . .
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