Notch Signaling Methods and Protocols
Notch Signaling: Methods and Protocols focuses on molecular, biochemical, and bioinformatics aspects of Notch signaling. Chapters analyze the Notch interactome, post-translational modifications of Notch, ligand binding assays, methods to assess proteolyti
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Hugo J. Bellen Shinya Yamamoto Editors
Notch Signaling Methods and Protocols
METHODS
IN
M O L E C U L A R B I O LO G Y
Series Editor John M. Walker School of Life Sciences University of Hertfordshire Hatfield, Hertfordshire, AL10 9AB, UK
For further volumes: http://www.springer.com/series/7651
Notch Signaling Methods and Protocols
Edited by
Hugo J. Bellen Department of Molecular and Human Genetics, Program in Developmental Biology, Department of Neuroscience, Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX, USA
Shinya Yamamoto Department of Molecular and Human Genetics, Program in Developmental Biology, Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, Baylor College of Medicine, Houston, TX, USA
Editors Hugo J. Bellen Department of Molecular and Human Genetics Program in Developmental Biology Department of Neuroscience Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital Howard Hughes Medical Institute Baylor College of Medicine Houston, TX, USA
Shinya Yamamoto Department of Molecular and Human Genetics Program in Developmental Biology Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital Baylor College of Medicine Houston, TX, USA
ISSN 1064-3745 ISSN 1940-6029 (electronic) ISBN 978-1-4939-1138-7 ISBN 978-1-4939-1139-4 (eBook) DOI 10.1007/978-1-4939-1139-4 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2014942725 © Springer Science+Business Media New York 2014 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed
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