Ocular Drug Delivery: Advances, Challenges and Applications
The eye is a highly specialized system of the body that has been designed with mechanisms for its own defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major cha
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Ocular Drug Delivery: Advances, Challenges and Applications
Ocular Drug Delivery: Advances, Challenges and Applications
Richard T. Addo Editor
Ocular Drug Delivery: Advances, Challenges and Applications
123
Editor Richard T. Addo School of Pharmacy Union University Jackson, TN USA
ISBN 978-3-319-47689-6 DOI 10.1007/978-3-319-47691-9
ISBN 978-3-319-47691-9
(eBook)
Library of Congress Control Number: 2016954017 © Springer International Publishing AG 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
To my wife, children and to God Almighty
Preface
Most people will agree with me that one of their greatest fears is losing their eyesight. Eye diseases affect the quality of life of hundreds of millions of individuals around the world. Scientists continue their search for the ideal ocular drug delivery system but they are still being faced with challenges due to the complex nature of the eye. This global observation and my research into ocular drug delivery gave birth to this book “Ocular Drug Delivery: Advances, Challenges, and Applications”. This book has detailed chapters that are comprised of various topics and issues pertinent to ocular therapeutic and drug delivery systems. It describes the anatomy of the eye with the barriers affecting the delivery of drug to it. The physiological barriers to drug delivery and the targeted delivery to specific compartments of the eye have also been discussed. Topical and systemic drug delivery to the eye has been compared. The delivery of proteins and peptides into the ocular cavity through novel delivery systems such as nano- and microparticles, nano micelles, and others that have been used to deliver drugs especially to the posterior segment of the eye has also been discussed with a detailed method of evalua
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