Pancreatic Disease Protocols and Clinical Research
Pancreatic Disease – Protocols and Clinical Research provides a clear and up-to-date review of the advancing areas in clinical pancreatology and clinical research related to the pancreas, and indentifies current research areas, suggesting most appropriate
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Pancreatic Disease Protocols and Clinical Research
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Pancreatic Disease
Colin D. Johnson • Clement W. Imrie Editors
Pancreatic Disease Protocols and Clinical Research
Editors Colin D. Johnson, MChir FRCS University Surgical Unit Southampton General Hospital Southampton UK
Clement W. Imrie, BSc MB ChB FRCS West of Scotland Pancreatic Unit Glasgow Royal Infirmary Glasgow UK
ISBN 978-1-84882-117-0 e-ISBN 978-1-84882-118-7 DOI 10.1007/978-1-84882-118-7 Springer London Dordrecht Heidelberg New York British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Control Number: 2009932718 © Springer-Verlag London Limited 2010 Apart from any fair dealing for the purposes of research or private study, or criticism or review, as permitted under the Copyright, Designs and Patents Act 1988, this publication may only be reproduced, stored or transmitted, in any form or by any means, with the prior permission in writing of the publishers, or in the case of reprographic reproduction in accordance with the terms of licences issued by the Copyright Licensing Agency. Enquiries concerning reproduction outside those terms should be sent to the publishers. The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant laws and regulations and therefore free for general use. Product liability: The publisher can give no guarantee for information about drug dosage and application thereof contained in this book. In every individual case the respective user must check its accuracy by consulting other pharmaceutical literature. Printed on acid-free paper Springer Science+Business Media springer.com
Contents
Part I Potential Trials in Acute Pancreatitis 1 Acute Pancreatitis in Intensive Care....................................................... John Kinsella, Barry Clements, Euan Dickson, Thierry Dugernier, and Martin Hughes 2 Antibiotic Prophylaxis in Acute Severe Pancreatitis: Should We Have a Further Study?......................................................... Jens Werner, Kevin C.P. Conlon, Hjalmar C. van Santvoort, Caroline S. Verbeke, and Sakhawat H. Rahman 3 Designing an Optimal Study for the Management of Infected Pancreatic Necrosis............................................................... Marc G.H. Besselink, Hjalmar C. van Santvoort, Ross Carter, Richard M. Charnley, Damian J. Mole, and Hein G. Gooszen 4 Nutrition in Acute Pancreatitis................................................................ Hemant M. Kocher, Christos Dervenis, Attila Oláh, William R. Murray, Barry Clements, and Clement W. Imrie 5 An Optimal Randomized Study for Pain Control in Acute Pancreatitis................................................................................. Åke Andrén-Sandberg, Julia V. Mayerle, Ajith K. Siriwardena, David P. Berry, Gareth R. Kirk, and Markus M. Lerch
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Part II Potential Trials in Chronic Pan
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