Pathogenicity Islands and PAI-Like Structures in Pseudomonas Species
The pseudomonads are a class of organisms which are ubiquitously distributed at low frequency in soil and aquatic habitats (OECD 1997). Some species (Pseudomonas putida, Pseudomonas fluorescens) are in addition profound colonizers of the rhizo- and phyllo
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Current Topics in Microbiology and Immunology
Editors R.W. Compans, Atlanta/Georgia M. Cooper, Birmingham/Alabama· Y. Ito, Kyoto H. Koprowski, Philadelphia/Pennsylvania· F. Melchers, Basel M. Old stone, La Jolla/California· S. Olsnes, Oslo M. Potter, Bethesda/Maryland P.K. Vogt, La Jolla/California· H. Wagner, Munich
Springer-Verlag Berlin Heidelberg GmbH
Pathogenicity Islands and the Evolution of Pathogenic Microbes Volume I
Edited by J. Hacker and J.B. Kaper
With 34 Figures and 7 Tables
,
Springer
Professor Or. JORG HACKER Universităt Wiirzburg Institut fUr Molekulare Infektionsbiologie R6ntgenring 11 97070 Wiirzburg Germany e-mail: [email protected] Professor Or. JAMES B. KAPER University of Maryland Schoo1 of Medicine Center for Vaccine Oeve1opment 685 W. Baltimore Street 21201 Baltimore, MO USA e-mail: [email protected]
Cover Illustration: Relative poslt1on on the S. enterica serovar Typhimurium LT-2 genetic map of virulence determÎnants which are absent from E. coli K-12. The large circle represents the chromosome, the small circle the virulence plasmid, pSLT. The positions of O and 100min are indicated. The sspH] and sopE] genes are absent from strain LT-2 but are present in other serovar Typhimurium isolates. (M1AO et al. 1999; M1ROLD et al. 1999).
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© Springer-Verlag Berlin Heidelberg 2002 Origina1ly published by Springer-Verlag Berlin Heidelberg New York in 2002 Softcover reprint of the hardcover 1st edition 2002 Library of Congress Catalog Card Number 15-12910 The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting other relevant litera ture. Cover Design: design & production GmbH, Heidelberg Typesetting: Scientific Publishing Services (P) Ltd, Madras Production Editor: Angelique Gcouta 27/3020 - 5 4 3 2 1 O Printed on acid-free paper SPIN: 10765335
Preface
In the year 1972 the famous evolutionary biologist Theodor
Dobzhansky wrote th