A retrospective chart review study of symptom onset, diagnosis, comorbidities, and treatment in patients with binge eati
- PDF / 699,271 Bytes
- 10 Pages / 595.276 x 790.866 pts Page_size
- 83 Downloads / 176 Views
ORIGINAL ARTICLE
A retrospective chart review study of symptom onset, diagnosis, comorbidities, and treatment in patients with binge eating disorder in Canadian clinical practice Simerpal K. Gill1 · Allan S. Kaplan2 Received: 16 April 2020 / Accepted: 21 September 2020 © The Author(s) 2020
Abstract Purpose In the Canadian healthcare setting, there is limited understanding of the pathways to diagnosis and treatment for patients with binge eating disorder (BED). Methods This retrospective chart review examined the clinical characteristics, diagnostic pathways, and treatment history of adult patients diagnosed with BED. Results Overall, 202 charts from 57 healthcare providers (HCPs) were reviewed. Most patients were women (69%) and white (78%). Mean ± SD patient age was 37 ± 12.1 years. Comorbidities identified in > 20% of patients included obesity (50%), anxiety (49%), depression and/or major depressive disorder (46%), and dyslipidemia (26%). Discussions regarding a diagnosis of BED were typically initiated more often by HCPs than patients. Most patients (64%) received a diagnosis of BED ≥ 3 years after symptom onset. A numerically greater percentage of patients received (past or current) nonpharmacotherapy than pharmacotherapy (84% vs. 67%). The mean ± SD number of binge eating episodes/week numerically decreased from pretreatment to follow-up with lisdexamfetamine (5.4 ± 2.8 vs. 1.7 ± 1.2), off-label pharmacotherapy (4.7 ± 3.9 vs. 2.0 ± 1.13), and nonpharmacotherapy (6.3 ± 4.8 vs. 3.5 ± 6.0) Across pharmacotherapies and nonpharmacotherapies, most patients reported improvement in symptoms of BED (84–97%) and in overall well-being (80–96%). Conclusions These findings highlight the importance of timely diagnosis and treatment of BED. Although HCPs are initiating discussions about BED, earlier identification of BED symptoms is required. Furthermore, these data indicate that pharmacologic and nonpharmacologic treatment for BED is associated with decreased binge eating and improvements in overall well-being. Level of evidence IV, chart review. Keywords Adult · Binge eating disorder · Diagnosis · Symptom onset · Treatment
Introduction Binge eating disorder (BED) is characterized by the recurrent consumption of an amount of food within a discrete period that is larger than what most people would eat, by a lack of control, and by marked distress over binge eating (BE) [1]. Studies suggest that BED has a neurobiologic * Simerpal K. Gill [email protected] 1
Bay Adelaide Centre, Medical Affairs, Takeda Canada Inc, 22 Adelaide Street West, Suite 3800, Toronto, ON M5H 4E3, Canada
Department of Psychiatry, University of Toronto, Toronto, ON, Canada
2
basis [2], with altered function in corticostriatal dopaminergic systems most likely playing a key role in the increased impulsivity and compulsivity, decreased reward sensitivity, and attentional biases toward food associated with BED [3]. The prevalence of BED based on Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria h
Data Loading...
