Biochemistry of the Eye
My first introduction to the eye came more than three decades ago when my close friend and mentor, the late Professor Isaac C. Michaelson, convinced me that studying the biochemistry of ocular tissues would be a rewarding pursuit. I hastened to explain th
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PERSPECTIVES IN VISION RESEARCH Series Editor: Colin Blakemore University of Oxford Oxford, England Biochemistry of the Eye Elaine R. Berman
Development ofthe Vertebrate Retina Edited by Barbara L. Finlay and Dale R. Sengelaub
Parallel Processing in the Visual System THE CLASSIFICATION OF RETINAL GANGLION CELLS AND ITS IMPACT ON THE NEUROBIOLOGY OF VISION Jonathan Stone
A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are bllled only upon actual shipment. For further information please contact the publisher.
Biochemistry of the Eye Elaine R. Berman Hadassah-Hebrew University Medical School Jerusalem, Israel
Springer Science+Business Media, LLC
LIbrary of Congress CatalogIng-In-PublIcatIon Data
Berman, Elaine R. Biochemistry of the eye I Elaine R. Berman. p. cm. -- (Perspectives in vision research) ISBN 978-1-4757-9443-4 ISBN 978-1-4757-9441-0 (eBook) DOI 10.1007/978-1-4757-9441-0
1. Eye--Physiology. 2. Biochemistry. I. Title. [DNLM, 1. Eye--chemlstry. WW 101 B51Sb] OP475.B4S 1991 S12.S·4--dc20 DNLM/DLC for Library of Congress
II. Series.
90-14353
CIP
© 1991 Springer Science+Business Media New York Originally published by Plenum Press, New York in 1991 Softcover reprint of the hardcover I st edition 1991 All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher
Dedicated to the memory of Professor Isaac C. Michaelson
Preface
My first introduction to the eye came more than three decades ago when my close friend and mentor, the late Professor Isaac C. Michaelson, convinced me that studying the biochemistry of ocular tissues would be a rewarding pursuit. I hastened to explain that I knew nothing about the subject, since relatively few basic biochemical studies on ocular tissues had appeared in the world literature. Professor Michaelson assured me, however, that two books on eye biochemistry had already been written. One of them, a beautiful monograph by Arlington Krause ( 1934) of Johns Hopkins Hospital, is we II worth reading even today for its historical perspective. The other, published 22 years later, was written by Antoinette Pirie and Ruth van Heyningen ( 1956), whose pioneering achievements in eye biochemistry at the Nuffield Laboratory of Ophthalmology in Oxford, England are known throughout the eye research community and beyond. To their credit are classical investigations on retinal, corneal, and lens biochemistry, beginning in the 1940s and continuing for many decades thereafter. Their important book written in 1956 on the Biochemistry of the Eye is a volume that stood out as a landmark in this field for many years. In recent years, however, a spectacular amount of new information has been generated in ocular biochemistry. Moreover, there is increasing specialization among investigators in
