Clinical Characteristics and Multisystem Imaging Findings of COVID-19: An Overview for Orthopedic Surgeons
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Clinical Characteristics and Multisystem Imaging Findings of COVID-19: An Overview for Orthopedic Surgeons Gireesh B. Reddy, MD & Dylan N. Greif, BA Harry G. Greditzer IV, MD & Jean Jose, DO
& Jose
Rodriguez, MD, PhD & Thomas M. Best, MD, PhD &
Received: 25 May 2020/Accepted: 8 July 2020/ * The Author(s) 2020
Abstract The COVID-19 pandemic holds widespread implications for global public health, economies, societies, and the practice of orthopedic surgery. As our knowledge of the transmissibility of SARS-CoV-2 and the symptomatology and management of COVID-19 expands, orthopedic surgeons must remain up to date on the latest medical evidence and surgical perspectives. While COVID-19 primarily manifests with pulmonary symptoms, cardiovascular, neurologic, and other major organ systems may also be affected and present with hallmark imaging findings. This article reviews initial and emerging literature on clinical characteristics and imaging findings of COVID-19. Keywords COVID-19 . coronavirus . diagnostic imaging . orthopedics
Electronic supplementary material The online version of this article (https://doi.org/10.1007/s11420-020-09775-3) contains supplementary material, which is available to authorized users. G. B. Reddy, MD : T. M. Best, MD, PhD Department of Orthopaedic Surgery, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL, USA J. Rodriguez, MD, PhD : J. Jose, DO Department of Radiology, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL, USA G. B. Reddy, MD : D. N. Greif, BA (*) : T. M. Best, MD, PhD : J. Jose, DO University of Miami Sports Medicine Institute, University of Miami Miller School of Medicine, Coral Gables, FL, USA e-mail: [email protected] H. G. Greditzer, IV, MD Department of Radiology, Hospital for Special Surgery, New York, NY, USA
Introduction Since December 2019, infections with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a novel betacoronavirus strain responsible for coronavirus disease 2019 (COVID-19), rapidly progressed from an isolated cluster of cases in the Hubei province of east central China to a pandemic, with significant global health and economic repercussions [4, 5, 10, 24, 25, 27, 28, 44, 58, 80, 91]. By mid-June 2020, the World Health Organization (WHO) had declared over 4.3 million people infected worldwide, with nearly 300,000 deaths. In the USA, despite unprecedented social distancing and public health measures, over 1.3 million people were infected, with more than 100,000 deaths [21]. Musculoskeletal chief complaints account for 18% of all healthcare visits in the USA [59], with nearly 23 million orthopedic procedures performed annually worldwide, of which five orthopedic procedures comprise 17% of all operations in the USA [4]. Public safety restrictions on semi-elective and elective office visits and surgical procedures during the COVID-19 pandemic have created a tremendous backlog (estimated at more than 1 million cases in 2 years) for ort
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