Lymphangiogenesis in Cancer Metastasis
Lymphangiogenesis and Cancer Metastasis introduces the new field of lymphatic vessel growth and development, and its relationship to the metastatic spread of cancer cells. The book covers all aspects of this new field from the fundamental role that protei
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Cancer Metastasis – Biology and Treatment VOLUME 13 Series Editors Richard J. Ablin, Ph.D., University of Arizona, College of Medicine and The Arizona Cancer Center, AZ, U.S.A. Wen G. Jiang, M.D., Wales College of Medicine, Cardiff University, Cardiff, U.K. Advisory Editorial Board Harold F. Dvorak, M.D. Phil Gold, M.D., Ph.D. Danny Welch, Ph.D. Hiroshi Kobayashi, M.D., Ph.D. Robert E. Mansel, M.S., FRCS. Klaus Pantel, Ph.D. Recent Volumes in this Series Volume 6: Bone Metastasis and Molecular Mechanisms Editors: Gurmit Singh and William Orr ISBN 978-1-4020-1984-X Volume 7: DNA Methylation, Epigenetics and Metastasis Editor: Manel Esteller ISBN 978-1-4020-3641-8 Volume 8: Cell Motility in Cancer Invasion and Metastasis Editor: Alan Wells ISBN 978-1-4020-4008-3 Volume 9: Cell Adhesion and Cytoskeletal Molecules in Metastasis Editors: Anne E. Cress and Raymond B. Nagle ISBN 978-1-4020-5128-X Volume 10: Metastasis of Prostate Cancer Editors: Richard J. Ablin and Malcolm D. Mason ISBN 978-1-4020-5846-2 Volume 11: Metastasis of Breast Cancer Editors: Robert E. Mansel, Oystein Fodstad and Wen G. Jiang ISBN 978-1-4020-5866-7 Volume 12: Bone Metastases: A Translational and Clinical Approach Editors: Dimitrios Kardamakis, Vassilios Vassiliou and Edward Chow ISBN 978-1-4020-9818-5 Volume 13: Lymphangiogenesis in Cancer Metastasis Editors: Steven A. Stacker and Marc G. Achen ISBN 978-90-481-2246-2
Lymphangiogenesis in Cancer Metastasis Edited by
Steven A. Stacker Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Parkville, Victoria, Australia and
Marc G. Achen Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Parkville, Victoria, Australia
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Editors Dr. Steven A. Stacker Ludwig Institute for Cancer Research Royal Melbourne Hospital Parkville, Victoria 3050 Australia [email protected]
ISBN: 978-90-481-2246-2
Dr. Marc G. Achen Ludwig Institute for Cancer Research Royal Melbourne Hospital Parkville, Victoria 3050 Australia [email protected]
e-ISBN: 978-90-481-2247-9
DOI 10.1007/978-90-481-2247-9 Library of Congress Control Number: 2009921270 c Springer Science+Business Media B.V. 2009 No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Printed on acid-free paper 9 8 7 6 5 4 3 2 1 springer.com
Contents
1 LYMPHANGIOGENESIS IN HEALTH AND DISEASE – AN OVERVIEW . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Steven A. Stacker, Marc G. Achen, Paula Haiko and Kari Alitalo
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2 INSIGHT INTO LYMPHATIC VASCULATURE DEVELOPMENT . 11 Nicole C. Johnson and Guillermo Oliver 3 NEW ANIMAL MODELS OF LYMPHANGIOGENESIS . . . . . . . . . . 27 Benjamin M. Hogan and Stefan Schulte-M
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