Raman Spectroscopy and Advanced Statistics for Cancer Diagnostics
While many cancers can be detected, current diagnostic efforts exhibit definite room for improvement. It is imperative that a person be diagnosed with cancer as early on in its progression as possible. An earlier diagnosis allows for the best treatment an
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imodal Optical Diagnostics of Cancer
Multimodal Optical Diagnostics of Cancer
Valery V. Tuchin • Jürgen Popp Valery Zakharov Editors
Multimodal Optical Diagnostics of Cancer
Editors Valery V. Tuchin Department of Optics and Biophotonics Saratov State University Saratov, Russia Valery Zakharov Department of Laser and Biotechnical Systems Samara National Research University Samara, Russia
Jürgen Popp Leibniz-Institute of Photonic Technology e.V. and Institute of Physical Chemistry and Abbe Center of Photonics University of Jena Jena, Thüringen, Germany
ISBN 978-3-030-44593-5 ISBN 978-3-030-44594-2 (eBook) https://doi.org/10.1007/978-3-030-44594-2 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
The purpose of this book is to outline the state-of-the-art optical approaches for the enhancement of medical diagnostics and earlier cancer detection and classification. The book brings together a description of the wide variety of optical techniques that have recently emerged for the specific study of the tumors of different organs and tissues. The appearance of this book was stimulated by the recent rapid progress in novel photonics technologies, the development of robust and cost-effective low- noise detectors and lasers, and fiber-optics devices. The multimodal approach provides a unique combination of structural, morphological, molecular, and metabolic information. The complexities of different methods of integration are compensated by the potential increase in both sensitivity and specificity of cancer diagnosis, screening, treatment monitoring, or image-guided intervention. The diagnosis of cancer is a complex process and requires a numb
