The role of prognostic nutritional index in the management of pulmonary sarcomatoid carcinoma
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Clinical Sarcoma Research Open Access
RESEARCH
The role of prognostic nutritional index in the management of pulmonary sarcomatoid carcinoma Yan Wang1* , Yu Cao2 and Junfeng Liu1
Abstract Background: Pulmonary sarcomatoid carcinoma is characterized by poor survival rates compared with other nonsmall cell lung cancer. Prognostic nutritional index has significant prognostic value in many malignant tumors. We conducted this retrospective study to investigate the role of prognostic nutritional index in patients with pulmonary sarcomatoid carcinoma and to determine prognostic factors. Methods: Of 8176 patients with resected lung cancer in a single high-volume institution between 2008 and 2015, 91 patients with pathologically diagnosed sarcomatoid carcinoma were included in our study and evaluated. Kaplan– Meier analysis and Cox regression analysis were conducted to analyze clinicopathologic data. Subgroup analysis of overall survival (OS) and recurrence-free survival (RFS) among pulmonary sarcomatoid carcinoma patients were also conducted. Results: Univariable analysis showed that tumor size (P = 0.018 in OS), and P = 0.021 in RFS), tumor stage(P
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